Noel G. McElvaney

University of North Carolina at Chapel Hill — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

85h-index25.2kcitations639works1.82yr avg
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Research Topics

Protease and Inhibitor Mechanisms(189), Cystic Fibrosis Research Advances(159), Peptidase Inhibition and Analysis(107), Neonatal Respiratory Health Research(96), Blood Coagulation and Thrombosis Mechanisms(69)

Publications637 total

179 Long term effects of elexacaftor/tezacaftor/ivacaftor on airway and systemic inflammation in cystic fibrosis over a five-year period
Journal of Cystic Fibrosis·2025
RNA editing to correct the Z-allele in models of alpha-1 antitrypsin deficiency allows for maintenance of acute phase response
2025
Severe Alpha-1 antitrypsin deficiency detected via Family Screening— Are never-smokers disease-free?
2025
Alpha-1 Antitrypsin Deficiency laboratory testing (AATD EARCO LABNet): External quality assessment
2025
Late Breaking Abstract - Real-world evidence for severe Alpha-1 Antitrypsin Deficiency: Life-years gained for augmentation therapy versus standard care
2025
Seasonal Changes in Circulating Alpha-1 Antitrypsin Are Altered by Sex and Genetic Deficiency
American Journal of Respiratory and Critical Care Medicine·2025
Education Research: ANSWER: A Multimodal Teaching Intervention for Neurology Undergraduate Medical Education
Neurology Education·2025Open Access
Research Priorities for Noninvasive Sampling of the Lower Respiratory Tract During Acute Respiratory Failure: An Official American Thoracic Society Workshop Report
Annals of the American Thoracic Society·2025· 2 citedOpen Access
Cystic Fibrosis Airway Mucus Hyperconcentration Produces a Vicious Cycle of Mucin, Pathogen, and Inflammatory Interactions that Promotes Disease Persistence.
UNC Libraries·2025Open Access
Longitudinal changes in the cystic fibrosis airway microbiota with time and treatment
UNC Libraries·2025Open Access
An update on targeting airway inflammation in cystic fibrosis
Expert Review of Respiratory Medicine·2025· 1 cited
EPS7.04Real world evaluation of the CF-ABLE score as a prognostic tool and clinical endpoint in cystic fibrosis
Journal of Cystic Fibrosis·2025
The Impact of Regional Air Quality and Social Deprivation Index on Lung Function in Individuals With Alpha-1 Antitrypsin Deficiency in Ireland: Analysis of National Alpha-1 Detection Programme, National Alpha-1 Registry, and National Ambient Air Quality Monitoring Network Data
American Journal of Respiratory and Critical Care Medicine·2025
SAT-338-YI The role of metabolic factors in alpha-1 antitrypsin deficiency
Journal of Hepatology·2025
Longitudinal Analysis of Alpha-1 Antitrypsin Patients on Augmentation Therapy
American Journal of Respiratory and Critical Care Medicine·2025
Sex Hormone Stimulation of CRISPR-modified HepG2 Cells Alters Alpha-1 Antitrypsin Production
American Journal of Respiratory and Critical Care Medicine·2025· 1 cited
Initial Characterization of the Alpha-1 Biomarker Consortium
American Journal of Respiratory and Critical Care Medicine·2025
Family Screening in Alpha-1 Antitrypsin Deficiency – Is It Enough?
American Journal of Respiratory and Critical Care Medicine·2025
Evaluating T Cell Subsets in Alpha-1 Antitrypsin Deficiency
American Journal of Respiratory and Critical Care Medicine·2025
Genetic Discrimination in Alpha-1 Antitrypsin Deficiency – An Emerging Barrier to Global Detection Efforts
American Journal of Respiratory and Critical Care Medicine·2025
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Frequent Co-authors

Catherine M. Greene(19), Shane O’Neill(16), Clifford C. Taggart(12), Ronald G. Crystal(8), Emer P. Reeves(7), Tomás P. Carroll(6), Sanjay H. Chotirmall(5), Oliver J. McElvaney(4), Cedric Gunaratnam(4), Robert A. Sandhaus(4), P. Birrer(4), Mark Brantly(4), David A. Bergin(4), Killian Hurley(3), Eeva Piitulainen(3), Richard C. Hubbard(3), Rodney L. Levine(3), Stephen G. J. Smith(3), Alan Mulgrew(3), Kevin Molloy(3)