Ramón Alajarı́n

Universidad de Alcalá — Spain

Chemistry · Physical Sciences

17h-index843citations51works0.02yr avg
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Research Topics

Synthesis and Biological Evaluation(8), Multicomponent Synthesis of Heterocycles(7), Microwave-Assisted Synthesis and Applications(7), Synthesis and bioactivity of alkaloids(5), Synthesis of heterocyclic compounds(5)

Publications51 total

Effects of a Losartan-Antioxidant Hybrid (GGN1231) on Vascular and Cardiac Health in an Experimental Model of Chronic Renal Failure
Nutrients·2023Open Access
Pyridazino-pyrrolo-quinoxalinium salts as highly potent and selective leishmanicidal agents targeting trypanothione reductase
European Journal of Medicinal Chemistry·2021· 9 citedOpen Access
Tripeptides as Integrin-Linked Kinase Modulating Agents Based on a Protein–Protein Interaction with α-Parvin
ACS Medicinal Chemistry Letters·2021· 7 citedOpen Access
Pyrrolo[1,2-a]quinoxal-5-inium salts and 4,5-dihydropyrrolo[1,2-a]quinoxalines: Synthesis, activity and computational docking for protein tyrosine phosphatase 1B
Bioorganic & Medicinal Chemistry·2021· 9 citedOpen Access
A Computer‐Driven Scaffold‐Hopping Approach Generating New PTP1B Inhibitors from the Pyrrolo[1,2‐<i>a</i>]quinoxaline Core
ChemMedChem·2021· 17 citedOpen Access
Pyrrolo[1,2‐<i>a</i>]quinoxalines: Insulin Mimetics that Exhibit Potent and Selective Inhibition against Protein Tyrosine Phosphatase 1B
ChemMedChem·2020Open Access
Pyrrolo[1,2‐<i>a</i>]quinoxalines: Insulin Mimetics that Exhibit Potent and Selective Inhibition against Protein Tyrosine Phosphatase 1B
ChemMedChem·2020· 17 cited
Preliminary research on 1-(4-bromo-2-nitroimidazol-1-yl)-3-[ 18 F]fluoropropan-2-ol as a novel brain hypoxia PET tracer in a rodent model of stroke
European Journal of Medicinal Chemistry·2015· 7 cited
Synthesis and biological evaluation of pyridazino[1′,6′:1,2]pyrido[3,4-b]indolinium and pyridazino[1,6-a]benzimidazolium salts as anti-inflammatory agents
European Journal of Medicinal Chemistry·2015· 12 citedOpen Access
N-(4-[18F]-fluoropyridin-2-yl)-N-{2-[4-(2-methoxyphenyl)piperazin-1-yl]ethyl}carboxamides as analogs of WAY100635. New PET tracers of serotonin 5-HT1A receptors
European Journal of Medicinal Chemistry·2014· 7 cited
Synthesis, modelling and biological characterization of 3-substituted-1H-indoles as ligands of GluN2B-containing N-methyl-d-aspartate receptors
Bioorganic & Medicinal Chemistry·2014· 22 citedOpen Access
ChemInform Abstract: Remote Aryl Cyanation via Isocyanide—Cyanide Rearrangement on Tosylmethyl Isocyanide Derivatives.
ChemInform·2013
Remote Aryl Cyanation via Isocyanide–Cyanide Rearrangement on Tosylmethyl Isocyanide Derivatives
Organic Letters·2013· 24 cited
Indole derivatives as dual-effective agents for the treatment of neurodegenerative diseases: Synthesis, biological evaluation, and molecular modeling studies
Bioorganic & Medicinal Chemistry·2013· 18 citedOpen Access
CCDC 929702: Experimental Crystal Structure Determination
The Cambridge Structural Database·2013Open Access
1H MRSI maps of tumor hypoxia using an extrinsic hypoxia probe
DIGITAL.CSIC (Spanish National Research Council (CSIC))·2013Open Access
New losartan-hydrocaffeic acid hybrids as antihypertensive-antioxidant dual drugs: Ester, amide and amine linkers
European Journal of Medicinal Chemistry·2012· 16 cited
ChemInform Abstract: Six‐Membered Heterocycles: Quinoline and Isoquinoline
ChemInform·2012
Six‐Membered Heterocycles: Quinoline and Isoquinoline
2011· 28 cited
An environmentally Benign Synthesis of 2-Cyanomethyl-4-Phenylthiazoles under FocusedMicrowave Irradiation
Green and Sustainable Chemistry·2011· 14 citedOpen Access
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Frequent Co-authors

Julio Álvarez‐Buílla(35), Juan J. Vaquero(34), Patricia Sánchez Alonso(10), Miguel Fau de Casa-Juana(7), Carlos Sunkel(7), Manuel Rodrı́guez-Puyol(7), Diego Rodrı́guez-Puyol(7), J. Sanz‐Aparicio(6), Mercedes Griera(6), Javier García‐Marín(6), Eduardo García‐Junceda(5), Carolina Burgos(5), I. Fonseca(4), Peter R. Statkow(4), Chi‐Huey Wong(4), Juan A. Vega(4), Jaime G. Priego(3), David Sucunza(3), Marta E. G. Mosquera(3), Miguel A. Pozo(3)