Chen-ya Chien

Medicine · Health Sciences

6h-index1.0kcitations12works0.02yr avg
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Research Topics

Influenza Virus Research Studies(5), RNA and protein synthesis mechanisms(5), interferon and immune responses(5), Infrared Thermography in Medicine(3), Protein Structure and Dynamics(1)

Publications12 total

Crystal structure of Klebsiella pneumoniae sigma4 of sigmaS fusing with the RNA polymerase beta-flap-tip-helix in complex with -35 element DNA
2018
Crystal structure of MERS-CoV macro domain in complex with AMP
2018
Crystal structure of MERS-CoV macro domain in complex with NAD
2018
Crystal structure of MERS-CoV macro domain in complex with ATP
2018
Biophysical Characterization of the Complex between Double-Stranded RNA and the N-Terminal Domain of the NS1 Protein from Influenza A Virus:  Evidence for a Novel RNA-Binding Mode
Biochemistry·2004· 122 cited
RNA binding by the novel helical domain of the influenza virus NS1 protein requires its dimer structure and a small number of specific basic amino acids
RNA·1999· 260 cited
Crystal structure of the unique RNA-binding domain of the influenza virus NS1 protein
Nature Structural & Molecular Biology·1997· 131 cited
A novel RNA-binding motif in influenza A virus non-structural protein 1
Nature Structural & Molecular Biology·1997· 126 cited
RNA-BINDING DOMAIN OF NON-STRUCTURAL PROTEIN 1 FROM INFLUENZA VIRUS, NMR, 16 STRUCTURES
1997
Automated analysis of protein NMR assignments using methods from artificial intelligence
Journal of Molecular Biology·1997· 311 cited
N-TERMINAL FRAGMENT OF NS1 PROTEIN FROM INFLUENZA A VIRUS
1997
An amino-terminal polypeptide fragment of the influenza virus NS1 protein possesses specific RNA-binding activity and largely helical backbone structure.
PubMed Central·1995· 99 citedOpen Access

Frequent Co-authors

G.T. Montelione(8), Robert M. Krug(6), Patricia A. Lynch(3), M.-H. Lin(3), Chang-Hui Cho(3), Ching‐Han Hsu(3), Diane E. Zimmerman(2), Yuanpeng J. Huang(2), Roberto Tejero(2), Casimir A. Kulikowski(1), Wenqing Feng(1), Mitsuru Tashiro(1), Sakurako Shimotakahara(1), Robert Powers(1), Weirong Wang(1), KELLY RIEDEL(1), Jinsong Liu(1), Helen M. Berman(1), Carlos B. Ríos(1), Yujia Xu(1)