Matthias Friedrich

University of St. Gallen — Switzerland

Biochemistry, Genetics and Molecular Biology · Life Sciences

39h-index8.1kcitations128works10.32yr avg
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Research Topics

Inflammatory Bowel Disease(23), Monoclonal and Polyclonal Antibodies Research(22), CAR-T cell therapy research(19), Immunotherapy and Immune Responses(15), Immune Cell Function and Interaction(12)

Publications128 total

Colonic folds as a unit for lymphatic drainage and immune surveillance supporting large intestinal outflow 3839
The Journal of Immunology·2025
XBB.1.5 COVID-19 mRNA Vaccines Induce Inadequate Mucosal Immunity in Patients with Inflammatory Bowel Disease
Vaccines·2025Open Access
CD4+ tissue-resident memory Th17 cells are a major source of IL-17A in Spondyloarthritis synovial tissue
Annals of the Rheumatic Diseases·2025· 8 citedOpen Access
STAR LIGHT Study: XBB.1.5 COVID-19 mRNA Vaccines Boost Systemic but Not Mucosal Immunity Against the SARS-CoV-2 JN.1 Variant in Patients with Chronic Liver Disease
Vaccines·2024· 2 citedOpen Access
<scp>XBB</scp>.1.5‐Adapted <scp>COVID</scp>‐19 <scp>mRNA</scp> Vaccines but Not Infections With Previous Omicron Variants Boost Neutralisation Against the <scp>SARS</scp>‐<scp>CoV</scp>‐2 <scp>JN</scp>.1 Variant in Patients With Inflammatory Bowel Disease
Alimentary Pharmacology & Therapeutics·2024· 8 citedOpen Access
A longitudinal single-cell atlas of anti-tumour necrosis factor treatment in inflammatory bowel disease
Nature Immunology·2024· 56 citedOpen Access
CD4+ tissue-resident memory Th17 cells are a major source of IL-17A in Spondyloarthritis synovial tissue
2024Open Access
Systemic and Mucosal Immunogenicity of Monovalent XBB.1.5-Adapted COVID-19 mRNA Vaccines in Patients with Inflammatory Bowel Disease
Vaccines·2024· 8 citedOpen Access
1189 Elucidating the effects of chemotherapy and immune checkpoint blockade on the activity of tarlatamab, a DLL3-targeting bispecific T cell engager molecule, in small cell lung cancer preclinical models
Regular and Young Investigator Award Abstracts·2023· 3 citedOpen Access
STAR SIGN study: Evaluation of COVID‐19 vaccine efficacy against the SARS‐CoV‐2 variants BQ.1.1 and XBB.1.5 in patients with inflammatory bowel disease
Alimentary Pharmacology & Therapeutics·2023· 11 cited
CLDN18.2 BiTE Engages Effector and Regulatory T Cells for Antitumor Immune Response in Preclinical Models of Pancreatic Cancer
Gastroenterology·2023· 18 citedOpen Access
MHC class II antigen presentation by intestinal epithelial cells fine-tunes bacteria-reactive CD4 T-cell responses
Mucosal Immunology·2023· 34 citedOpen Access
A longitudinal single-cell therapeutic atlas of anti-tumour necrosis factor treatment in inflammatory bowel disease
2023· 10 citedOpen Access
629 A SINGLE-CELL THERAPEUTIC ATLAS OF ANTI-TUMOUR NECROSIS FACTOR THERAPY IN INFLAMMATORY BOWEL DISEASE
Gastroenterology·2023· 1 citedOpen Access
Adipocyte autophagy limits gut inflammation by controlling oxylipin and <scp>IL‐10</scp>
The EMBO Journal·2023· 26 citedOpen Access
MHC class II antigen presentation by intestinal epithelial cells fine-tunes bacteria-reactive CD4 T cell responses
2023· 3 citedOpen Access
A conserved population of MHC II-restricted, innate-like, commensal-reactive T cells in the gut of humans and mice
Nature Communications·2022· 17 citedOpen Access
WITHDRAWN: Anti-TNF-induced IL-27 modulates regulatory T cell responses in patients with IBD that respond to therapy
2022· 2 citedOpen Access
Shining a Light on Barrier Function
Gastroenterology·2022· 3 citedOpen Access
Systemic and T cell‐associated responses to <scp>SARS‐CoV</scp>‐2 immunisation in gut inflammation (<scp>STAR SIGN</scp> study): effects of biologics on vaccination efficacy of the third dose of <scp>mRNA</scp> vaccines against <scp>SARS‐CoV</scp>‐2
Alimentary Pharmacology & Therapeutics·2022· 16 citedOpen Access
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Frequent Co-authors

Fiona Powrie(14), Stephan Brand(11), Florian Beigel(9), Tobias Raum(9), Julia Diegelmann(8), Mathilde Pohin(7), Cornelia Tillack(7), Johannes Stallhofer(7), Jürgen Glas(7), Benno Rattel(7), Peter Kufer(7), Martin Wetzke(6), Roman Kischel(6), Patrick A. Baeuerle(6), Joachim Wahl(6), Torsten Olszak(6), Burkhard Göke(6), Sarah McCuaig(5), Oliver S. Thomas(5), Angela Coxon(5)