Robert L. LaFemina

Serendipity Innovations (Sweden) — Sweden

Medicine · Health Sciences

23h-index3.2kcitations35works0.02yr avg
OpenAlex↗Google Scholar↗Lab page↗

Accepting Students?

No reports yet. Know if this professor is taking students?

Research Topics

HIV/AIDS drug development and treatment(12), Herpesvirus Infections and Treatments(11), Cytomegalovirus and herpesvirus research(11), Hepatitis C virus research(9), Hepatitis B Virus Studies(7)

Publications35 total

Alternative Screening Approaches for Discovery of Middle East Respiratory Syndrome Coronavirus Inhibitors
Antimicrobial Agents and Chemotherapy·2014· 8 citedOpen Access
Nucleoside Analog Inhibitors of Hepatitis C Viral Replication
Antiviral Research·2014· 1 cited
Antiviral research: strategies in antiviral drug discovery.
ASM Press eBooks·2009· 23 cited
Hepatitis C Virus Genetics and the Discovery of Mechanism-Based Inhibitors of the NS3/4A Protease and NS5B Polymerase
Translational research in biomedicine·2008
A genotype 2b NS5B polymerase with novel substitutions supports replication of a chimeric HCV 1b:2b replicon containing a genotype 1b NS3-5A background
Antiviral Research·2005· 14 cited
Replication Fitness and NS5B Drug Sensitivity of Diverse Hepatitis C Virus Isolates Characterized by Using a Transient Replication Assay
Antimicrobial Agents and Chemotherapy·2005· 117 citedOpen Access
CCDC 245444: Experimental Crystal Structure Determination
The Cambridge Structural Database·2005Open Access
A 7-Deaza-Adenosine Analog Is a Potent and Selective Inhibitor of Hepatitis C Virus Replication with Excellent Pharmacokinetic Properties
Antimicrobial Agents and Chemotherapy·2004· 233 citedOpen Access
Structure−Activity Relationship of Heterobase-Modified 2‘-<i>C</i>-Methyl Ribonucleosides as Inhibitors of Hepatitis C Virus RNA Replication
Journal of Medicinal Chemistry·2004· 185 cited
Characterization of Resistance to Non-obligate Chain-terminating Ribonucleoside Analogs That Inhibit Hepatitis C Virus Replication in Vitro
Journal of Biological Chemistry·2003· 324 citedOpen Access
An in vitro Flaviviridae replicase system capable of authentic RNA replication
Virology·2003· 17 cited
Inhibition of Hepatitis C Virus RNA Replication by 2′-Modified Nucleoside Analogs
Journal of Biological Chemistry·2003· 336 citedOpen Access
Characterization of a soluble stable human cytomegalovirus protease and inhibition by M-site peptide mimics
Journal of Virology·1996· 24 citedOpen Access
Sequence within the HIV-1 LTR required for strand transfer by integrase in vitro
Antiviral Research·1995
Inhibition of human immunodeficiency virus integrase by bis-catechols
Antimicrobial Agents and Chemotherapy·1995· 73 citedOpen Access
Purification of active herpes simplex virus-1 protease expressed in Escherichia coli.
Journal of Biological Chemistry·1994· 39 citedOpen Access
Peptide substrate cleavage specificity of the human cytomegalovirus protease.
Journal of Biological Chemistry·1994· 57 citedOpen Access
Viral long terminal repeat substrate binding characteristics of the human immunodeficiency virus type 1 integrase.
Journal of Biological Chemistry·1994· 46 citedOpen Access
Requirement of active human immunodeficiency virus type 1 integrase enzyme for productive infection of human T-lymphoid cells
Journal of Virology·1992· 261 citedOpen Access
Structural implications of spectroscopic characterization of a putative zinc finger peptide from HIV-1 integrase.
Journal of Biological Chemistry·1992· 170 citedOpen Access
page 1 of 2Next →

Frequent Co-authors

Daria J. Hazuda(8), David B. Olsen(7), Steven S. Carroll(6), Joanne E. Tomassini(6), Krista Getty(6), B. Wolanski(6), Osvaldo Flores(6), Gary S. Hayward(6), Anne B. Eldrup(5), Balkrishen Bhat(5), Michele Bosserman(4), Mark W. Stahlhut(4), Malcolm MacCoss(4), Lawrence F. Colwell(4), K LeGrow(4), Emilio A. Emini(4), Giovanni Migliaccio(3), Steven W. Ludmerer(3), Daniel R. McMasters(3), H.L. Robbins(3)