Iris Helfrich

German Cancer Research Center — Germany

Biochemistry, Genetics and Molecular Biology · Life Sciences

33h-index4.9kcitations151works1.12yr avg
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Research Topics

Angiogenesis and VEGF in Cancer(37), Radiopharmaceutical Chemistry and Applications(23), Nanoplatforms for cancer theranostics(21), Barrier Structure and Function Studies(20), Cancer Cells and Metastasis(18)

Publications151 total

Supplementary Data from Active Remodeling of Capillary Endothelium via Cancer Cell–Derived MMP9 Promotes Metastatic Brain Colonization
2025Open Access
Supplementary Data from Active Remodeling of Capillary Endothelium via Cancer Cell–Derived MMP9 Promotes Metastatic Brain Colonization
2025Open Access
Supplementary Data from Active Remodeling of Capillary Endothelium via Cancer Cell–Derived MMP9 Promotes Metastatic Brain Colonization
2025Open Access
Supplementary Data from Active Remodeling of Capillary Endothelium via Cancer Cell–Derived MMP9 Promotes Metastatic Brain Colonization
2025Open Access
Supplementary Data from Active Remodeling of Capillary Endothelium via Cancer Cell–Derived MMP9 Promotes Metastatic Brain Colonization
2025Open Access
Supplementary Data from Active Remodeling of Capillary Endothelium via Cancer Cell–Derived MMP9 Promotes Metastatic Brain Colonization
2025Open Access
Supplementary Data from Active Remodeling of Capillary Endothelium via Cancer Cell–Derived MMP9 Promotes Metastatic Brain Colonization
2025Open Access
Identification and characterization of tertiary lymphoid structures in brain metastases
Acta Neuropathologica Communications·2025· 1 citedOpen Access
Serpins A1/A3 within tumor-derived extracellular vesicles support pro-tumoral bias of neutrophils in cancer
2025· 1 citedOpen Access
RECQL4 affects MHC class II‐mediated signalling and favours an immune‐evasive signature that limits response to immune checkpoint inhibitor therapy in patients with malignant melanoma
Clinical and Translational Medicine·2025· 1 citedOpen Access
Spatial proteomics reveals sirtuin 1 to be a determinant of T-cell infiltration in human melanoma
British Journal of Dermatology·2024· 5 cited
Structure-based discovery of first inhibitors targeting the helicase activity of human PIF1
Nucleic Acids Research·2024· 10 citedOpen Access
T lymphocyte recruitment to melanoma brain tumors depends on distinct venous vessels
Immunity·2024· 15 citedOpen Access
Identification and characterization of tertiary lymphoid structures in brain metastases
2024· 1 citedOpen Access
Supplementary Data from Active remodeling of capillary endothelium via cancer cell-derived MMP9 promotes metastatic brain colonization
2024Open Access
Supplementary Data from Active remodeling of capillary endothelium via cancer cell-derived MMP9 promotes metastatic brain colonization
2024Open Access
Supplementary Data from Active remodeling of capillary endothelium via cancer cell-derived MMP9 promotes metastatic brain colonization
2024Open Access
Supplementary Data from Active remodeling of capillary endothelium via cancer cell-derived MMP9 promotes metastatic brain colonization
2024Open Access
Supplementary Data from Active remodeling of capillary endothelium via cancer cell-derived MMP9 promotes metastatic brain colonization
2024Open Access
Supplementary Data from Active remodeling of capillary endothelium via cancer cell-derived MMP9 promotes metastatic brain colonization
2024Open Access
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Frequent Co-authors

Dirk Schadendorf(26), Hellmut G. Augustin(7), Alexander Roesch(6), Stefanie Löffek(6), Christian Stockmann(5), Antje Sucker(5), Susanne Horn(5), Stefan Mueller‐Lissner(4), Matthias Gunzer(4), Dirk M. Hermann(4), Bernhard B. Singer(4), Nico Ullrich(4), Michael Hölzel(3), Ingo Stoffels(3), Joachim Klode(3), Inka Scheffrahn(3), Ralph Klose(3), Sebastian Korste(3), Elisabeth Livingstone(3), Selma Ugurel(3)