S. Flodin

Karolinska Institutet — Sweden

Biochemistry, Genetics and Molecular Biology · Life Sciences

17h-index1.1kcitations131works0.02yr avg
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Research Topics

Biochemical and Molecular Research(40), Folate and B Vitamins Research(10), RNA Research and Splicing(9), Enzyme Structure and Function(9), HIV/AIDS drug development and treatment(8)

Publications131 total

Structural Basis for the Specificity of Human NUDT16 and Its Regulation by Inosine Monophosphate
PLoS ONE·2015· 25 citedOpen Access
Structural Basis for Phosphoinositide Substrate Recognition, Catalysis, and Membrane Interactions in Human Inositol Polyphosphate 5-Phosphatases
Structure·2014· 62 cited
Substrate Specificity and Oligomerization of Human GMP Synthetase
Journal of Molecular Biology·2013· 39 citedOpen Access
Pan-Pathway Based Interaction Profiling of FDA-Approved Nucleoside and Nucleobase Analogs with Enzymes of the Human Nucleotide Metabolism
PLoS ONE·2012· 19 citedOpen Access
HUMAN GUANINE DEAMINASE IN COMPLEX WITH VALACYCLOVIR
2012
Cofactor mobility determines reaction outcome in the IMPDH and GMPR (β-α)8 barrel enzymes
Nature Chemical Biology·2011· 36 cited
Human Myotubularin related protein 6 (MTMR6)
2011
Structural basis for allosteric regulation of human ribonucleotide reductase by nucleotide-induced oligomerization
Nature Structural & Molecular Biology·2011· 174 citedOpen Access
BRICHOS domain of Surfactant protein C precursor protein
2011
Crystal structure of the NTF2 domain of Ras GTPase-activating protein-binding protein 1
2011
Crystal Structure of Human 8-oxo-dGTPase (MTH1)
2011· 2 cited
Crystal Structure of Human Uridine Diphosphate Glucose Pyrophosphatase (NUDT14)
2011· 1 cited
HUman PARP14 (ARTD8)-Macro domain 1 in complex with adenosine-5-diphosphoribose
2011
Structural and functional studies of the human phosphoribosyltransferase domain containing protein 1
FEBS Journal·2010· 17 cited
Crystal structure of human Nudix motif 16 (NUDT16) in complex with IMP and magnesium
2010
Nischarin PX-domain
2010
CRYSTAL STRUCTURE OF THE RHOGAP DOMAIN OF HUMAN PIK3R2
2010
The Crystal Structure of the Dachshund Domain of Human SnoN Reveals Flexibility in the Putative Protein Interaction Surface
PLoS ONE·2010· 14 citedOpen Access
Crystal structure of human uridine phosphorylase 2
2010
Structural studies of tri-functional human GART
Nucleic Acids Research·2010· 40 citedOpen Access
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Frequent Co-authors

P. Nordlund(49), T. Nyman(41), S. Gräslund(35), M. Hammarstrom(34), T. Kotenyova(33), H. Berglund(30), M. Welin(29), L. Tresaugues(27), M. Moche(25), C.H. Arrowsmith(25), T. Karlberg(25), J. Weigelt(24), Pål Stenmark(22), J. Sagemark(22), L. Lehtiö(20), A.G. Thorsell(19), A.M. Edwards(18), I. Johansson(17), L.G. Dahlgren(16), S. Van Den Berg(16)