Claus Bornæs

Orphazyme (Denmark) — Denmark

Medicine · Health Sciences

4h-index321citations7works0.02yr avg
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Research Topics

Lysosomal Storage Disorders Research(3), Cellular transport and secretion(2), Endoplasmic Reticulum Stress and Disease(2), Breast Cancer Treatment Studies(1), Lipid Membrane Structure and Behavior(1)

Publications7 total

The heat shock protein amplifier arimoclomol improves refolding, maturation and lysosomal activity of glucocerebrosidase
EBioMedicine·2018· 46 citedOpen Access
Arimoclomol as a potential therapy for neuronopathic Gaucher Disease
2018· 1 citedOpen Access
Arimoclomol, a clinical candidate for neuronopathic Gaucher disease, increases glucocerebrosidase activity through amplification of heat shock proteins
Molecular Genetics and Metabolism·2018
Heat shock protein-based therapy for sphingolipidoses
Molecular Genetics and Metabolism·2017· 1 cited
Heat shock protein–based therapy as a potential candidate for treating the sphingolipidoses
Science Translational Medicine·2016· 172 cited
Development of a Transgenic Mouse Model Immune Tolerant for Human Interferon Beta
Pharmaceutical Research·2005· 71 cited
A Regulatory Element in the <i>CHA1</i> Promoter Which Confers Inducibility by Serine and Threonine on <i>Saccharomyces cerevisiae</i> Genes
Molecular and Cellular Biology·1993· 30 citedOpen Access

Frequent Co-authors

Thomas Kirkegaard(5), Nikolaj H.T. Petersen(5), Paola Zago(3), Erika Malini(3), Lukasz M. Solanko(3), Raffaella Magnoni(3), Bruno Bembi(3), Andrea Dardis(3), James Gray(2), David A. Priestman(2), Jennifer Atkins(2), Ole Dines Olsen(2), Alexander Klein(2), Svetlana Drndarski(2), Linda Ingemann(2), David A. Smith(2), Signe Humle Jørgensen(2), Anders M. Hinsby(2), Christoph Arenz(2), David J. Begley(2)