Kenju Shimomura

Universidade Federal do Rio Grande do Sul — Brazil

Medicine · Health Sciences

37h-index4.7kcitations162works1.62yr avg
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Research Topics

Pancreatic function and diabetes(51), Neuroendocrine regulation and behavior(20), Regulation of Appetite and Obesity(16), Cardiac Ischemia and Reperfusion(15), Hyperglycemia and glycemic control in critically ill and hospitalized patients(14)

Publications161 total

Oxytocin Enhances Demethylation Through <scp>TET</scp> Enzyme Expression in Neurons of Aged Mice: Oxytocin as a Potential Antiaging Peptide
Aging Cell·2025· 3 citedOpen Access
Kir6.2 channel activity is regulated by interaction of transmembrane domains 1 and 2 through <scp>I167</scp> in the bundle‐crossing gate
Physiological Reports·2025Open Access
Kamikihito ameliorates social recognition in oxytocin gene deficient mice and environmentally induced autism spectrum disorder model mice
Journal of Ethnopharmacology·2025
Prediction of possible new drug binding site for ATP-sensitive potassium channel inhibition: bupropion’s modulation of hippocampal CA1 neuron excitability
Neuroreport·2025
Oxytocin modulates insulin and GLP-1 secretion in pancreatic islets
Aging·2025Open Access
β‐Adrenergic Blockers Increase <scp>cAMP</scp> and Stimulate Insulin Secretion Through a <scp>PKA</scp> / <scp>RYR2</scp> / <scp>TRPM5</scp> Pathway in Pancreatic β‐Cells In Vitro
Pharmacology Research & Perspectives·2025· 2 citedOpen Access
Canagliflozin‐induced renal glutathione distribution mapping in non‐diabetic male rat kidneys
Physiological Reports·2025· 1 citedOpen Access
Pyruvate kinase modulates the link between β‐cell fructose metabolism and insulin secretion
The FASEB Journal·2025· 5 citedOpen Access
Editorial: Endocrinology of obesity, aging and stress
Frontiers in Endocrinology·2025Open Access
Experimenters' sex modulates anxiety-like behavior, contextual fear, and microglial oxytocin transcription in mice
Behavioural Brain Research·2025· 4 citedOpen Access
Increased use of psychiatric drugs in Brazil over the years: evidence from a country-wide dataset
Trends in Psychiatry and Psychotherapy·2025Open Access
Ficus pumila L. Improves Lower Urinary Tract Symptoms in Patients with Benign Prostatic Hyperplasia After COVID-19 Infection
Preprints.org·2024Open Access
Limited Sampling Strategy for Predicting the Area under Plasma Concentration–Time Curve of Nadolol in Healthy Subjects
The Journal of Clinical Pharmacology·2024
β-adrenergic blockers increase cAMP and stimulate insulin secretion through a PKA/RYR2/TRPM5 pathway in pancreatic β-cells in vitro
2024Open Access
The release of <scp>GLP</scp>‐1 from gut L cells is inhibited by low extracellular <scp>pH</scp>
Obesity·2024· 3 citedOpen Access
Pyruvate kinase modulates the link between β-cell fructose metabolism and insulin secretion
2024· 2 citedOpen Access
Peripheral dopamine suppression and elevated cystatin C in early diabetic nephropathy in spontaneously diabetic rats
American Journal of Physiology-Renal Physiology·2024· 2 cited
Sildenafil amplifies calcium influx and insulin secretion in pancreatic β cells
Physiological Reports·2024· 7 citedOpen Access
Chemogenetic activation of mammalian brain neurons expressing insect Ionotropic Receptors by systemic ligand precursor administration
Communications Biology·2024· 1 citedOpen Access
Traditional Japanese medicine Kamikihito ameliorates sucrose preference, chronic inflammation and obesity induced by a high fat diet in middle-aged mice
Frontiers in Endocrinology·2024· 2 citedOpen Access
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Frequent Co-authors

Frances M. Ashcroft(16), Yuko Maejima(15), Peter Proks(9), Roger Cox(7), Patrik Rorsman(7), Christophe A. Girard(5), Hiroyuki Shimizu(5), Helen Freeman(4), Sian Ellard(4), Andrew T. Hattersley(4), Stephan C. Collins(4), Katsuhiko Nishimori(4), Toshihiko Yada(4), Seiichi Takenoshita(4), Masatomo Mori(4), Masatomo Mori(4), Michelle Goldsworthy(3), Melissa F. Brereton(3), Michaela Iberl(3), Quan Zhang(3)