Toshimitsu Niwa

Shubun University — Japan

Biochemistry, Genetics and Molecular Biology · Life Sciences

66h-index15.9kcitations462works4.22yr avg
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Research Topics

Advanced Glycation End Products research(68), Dialysis and Renal Disease Management(65), Metabolism and Genetic Disorders(45), Estrogen and related hormone effects(35), Chronic Kidney Disease and Diabetes(33)

Publications456 total

Indoxyl Sulfate in the Gut–Kidney Axis: Pathophysiology and Clinical Significance in CKD-Associated Colorectal Cancer
Toxins·2026Open Access
Improvement of bending formability of AZX612 magnesium alloy by surface texture control utilizing shot peening
Materials Characterization·2025Open Access
The Role of Indoxyl Sulfate in Exacerbating Colorectal Cancer During Chronic Kidney Disease Progression: Insights into the Akt/β-Catenin/c-Myc and AhR/c-Myc Pathways in HCT-116 Colorectal Cancer Cells
Toxins·2025· 8 citedOpen Access
Improvement of Bending Formability of Azx612 Magnesium Alloy by Surface Texture Control Utilizing Shot Peening
SSRN Electronic Journal·2025Open Access
Serum Fructosamine as a Marker for Glycemic Control in Patients with Diabetic Nephropathy
Proceedings of the Bulgarian Academy of Sciences·2024· 2 citedOpen Access
Indoxyl sulfate contributes to colorectal cancer cell proliferation and increased EGFR expression by activating AhR and Akt
Biomedical Research·2024· 15 citedOpen Access
Antiglycation properties of resveratrol and glucosamine
Journal of Chemical Technology and Metallurgy·2023· 2 citedOpen Access
Indoxyl Sulfate Activates NLRP3 Inflammasome to Induce Cardiac Contractile Dysfunction Accompanied by Myocardial Fibrosis and Hypertrophy
Cardiovascular Toxicology·2022· 39 cited
NanoLuc luciferase as a suitable fusion partner of recombinant antibody fragments for developing sensitive luminescent immunoassays
Analytica Chimica Acta·2021· 23 cited
Clinical impact of triglyceride deposit cardiomyovasculopathy, coronary atherosclerosis with triglyceride deposition, on vascular failure after drug-eluting stent implantation
European Heart Journal·2020
Decreased ER dependency after acquired resistance to CDK4/6 inhibitors
Breast Cancer·2020· 19 cited
Characterization of a membrane-associated estrogen receptor in breast cancer cells and its contribution to hormone therapy resistance using a novel selective ligand
The Journal of Steroid Biochemistry and Molecular Biology·2020· 2 cited
Effects of the oral adsorbent AST-120 on fecal p-cresol and indole levels and on the gut microbiota composition
Biochemical and Biophysical Research Communications·2020· 28 cited
Abstract P6-04-26: PI3K inhibitors restored the sensitivity to anti-estrogen drugs in endocrine therapy resistant cell lines
Cancer Research·2020
Abstract PD2-04: Different mechanism of CDK4/6 inhibitor resistance between ribociclib and abemaciclib
Cancer Research·2020· 3 cited
Indoxyl Sulfate-induced Vascular Calcification is mediated through Altered Notch Signaling Pathway in Vascular Smooth Muscle Cells
International Journal of Medical Sciences·2020· 12 citedOpen Access
Overview of Uremic Toxins
2020· 2 cited
Pyogenic spondylitis with acute course caused by Corynebacterium simulans
Journal of Infection and Chemotherapy·2019· 12 cited
Medical mass spectrometrist (MMS) training and certification: A key step to expanding routine clinical mass spectrometry usage in Japan
Clinical mass spectrometry·2019· 4 cited
Correction to “‘Breeding’ Diagnostic Antibodies for Higher Assay Performance: A 250-Fold Affinity-Matured Antibody Mutant Targeting a Small Biomarker”
Analytical Chemistry·2019· 3 citedOpen Access
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Frequent Co-authors

Atsushi Enomoto(12), Hidehisa Shimizu(10), Fuyuhiko Nishijima(10), Hitoshi Endou(6), Michio Takeda(5), Fumio Takayama(5), Dilinaer Bolati(5), Kentaro Taki(5), Seok Ho(4), Ayinuer Adijiang(4), Takashi Miyazaki(4), Yukihiro Higashiyama(4), Takashi Sekine(3), Yoshiharu Itoh(3), Atsuko Ezawa(3), Kaori Kikuchi(3), Yoshinari Tsuruta(3), Gulinuer Muteliefu(3), Maimaiti Yisireyili(3), Promsuk Jutabha(2)