Luca Fornelli

University of Oklahoma — United States

Chemistry · Physical Sciences

36h-index4.3kcitations104works3.62yr avg
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Research Topics

Mass Spectrometry Techniques and Applications(65), Advanced Proteomics Techniques and Applications(57), Analytical Chemistry and Chromatography(23), Metabolomics and Mass Spectrometry Studies(19), Protein purification and stability(14)

Publications104 total

On the Utility of Infrared Photoactivation for Native Top-Down and Complex-Down Orbitrap Mass Spectrometry of Soluble Proteoform Complexes
Journal of the American Society for Mass Spectrometry·2026Open Access
Mechanosensor-mediated Hsp70 phosphorylation orchestrates the landscape of the heat shock response
Nature Communications·2025· 1 citedOpen Access
Comparative Analysis of Proteoform Clean‐Up Methods for In‐Depth Top‐Down Proteomics
PROTEOMICS·2025· 1 citedOpen Access
Automating Mass Spectrometry Data Analysis for Antibody Subunit Characterization
2025
Sample preparation and cleanup methods for clinical top-down proteomics
Expert Review of Proteomics·2025· 1 citedOpen Access
Comparative Analysis of Proteoform Clean-Up Methods for Improved Top-Down Proteomics
2025Open Access
Blocking C-terminal processing of KRAS4b via a direct covalent attack on the CaaX-box cysteine
Proceedings of the National Academy of Sciences·2025· 3 citedOpen Access
Gel-Based Sample Fractionation with SP3-Purification for Top-Down Proteomics
Journal of Proteome Research·2025· 3 citedOpen Access
Acetylation of the yeast Hsp40 chaperone protein Ydj1 fine-tunes proteostasis and translational fidelity
PLoS Genetics·2024· 10 citedOpen Access
Enhanced Payload Localization in Antibody–Drug Conjugates Using a Middle-Down Mass Spectrometry Approach with Proton Transfer Charge Reduction
Analytical Chemistry·2024· 6 citedOpen Access
Leveraging Ion–Ion and Ion–Photon Activation to Improve the Sequencing of Proteins Carrying Multiple Disulfide Bonds: The Human Serum Albumin Case Study
Journal of the American Society for Mass Spectrometry·2024· 4 citedOpen Access
Gel-Based Sample Fractionation with SP3-Purification for Top-Down Proteomics
2024Open Access
Towards a universal method for middle-down analysis of antibodies via proton transfer charge reduction—Orbitrap mass spectrometry
Analytical and Bioanalytical Chemistry·2024· 8 citedOpen Access
Top‐down mass spectrometry analysis of capsid proteins of recombinant adeno‐associated virus using multiple ion activations and proton transfer charge reduction
PROTEOMICS·2024· 7 citedOpen Access
Characterization of a Monoclonal Antibody by Native and Denaturing Top-Down Mass Spectrometry
Journal of the American Society for Mass Spectrometry·2024· 8 citedOpen Access
Leveraging ion-ion and ion-photon reactions to improve the sequencing of proteins carrying multiple disulfide bonds: the human serum albumin case study
2024· 1 citedOpen Access
Enhanced payload localization in antibody-drug conjugates using a middle-down mass spectrometry approach with proton transfer charge reduction
2024· 1 citedOpen Access
Towards a universal method for middle-down analysis of antibodies via proton transfer charge reduction – Orbitrap mass spectrometry
2024· 1 citedOpen Access
Top-down mass spectrometry analysis of capsid proteins of recombinant adeno-associated virus using multiple ion activations and proton transfer charge reduction
2024· 1 citedOpen Access
Acetylation of the yeast Hsp40 chaperone protein Ydj1 fine-tunes proteostasis and translational fidelity
2024Open Access
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Frequent Co-authors

Neil L. Kelleher(26), Yury O. Tsybin(17), Ryan T. Fellers(15), Kristina Srzentić(14), Philip D. Compton(11), Kenneth R. Durbin(9), Timothy K. Toby(8), Peter F. Doubleday(8), Romain Huguet(8), Caroline J. DeHart(7), Rafael D. Melani(7), Henrique S. Seckler(7), Richard D. LeDuc(7), Joseph B. Greer(7), Alain Beck(6), Paul M. Thomas(5), Christopher Mullen(5), Vlad Zabrouskov(5), Jake Kline(5), Daniel Ayoub(4)