Miriam Linsenmeier

California University of Pennsylvania — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

14h-index1.1kcitations38works7.02yr avg
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Research Topics

RNA Research and Splicing(16), Amyotrophic Lateral Sclerosis Research(7), Innovative Microfluidic and Catalytic Techniques Innovation(7), Prion Diseases and Protein Misfolding(6), RNA modifications and cancer(6)

Publications38 total

Nuclear-import receptors remodel the dilute phase to suppress phase transitions of RNA-binding proteins with prion-like domains
2025Open Access
Scouring the human Hsp70 network uncovers diverse chaperone safeguards buffering TDP-43 toxicity
2025· 1 citedOpen Access
BPS2025 - Chaperoning functions of beta-importin TNPO1 are realized by its ability to modulate the phase behaviors of cargo proteins
Biophysical Journal·2025
Short RNA chaperones promote aggregation-resistant TDP-43 conformers to mitigate neurodegeneration
2024· 4 citedOpen Access
An evolutionarily conserved mechanism controls reversible amyloids of pyruvate kinase via pH-sensing regions
Developmental Cell·2024· 17 citedOpen Access
Nuclear-import receptor TNPO1 as modulator of aberrant phase transitions
Biophysical Journal·2024
Nuclear-import receptors as gatekeepers of pathological phase transitions in ALS/FTD
Molecular Neurodegeneration·2024· 27 citedOpen Access
The interface of condensates of the hnRNPA1 low-complexity domain promotes formation of amyloid fibrils
Nature Chemistry·2023· 162 citedOpen Access
Linsenmeier_hnRNPA1-interface_SourceData_SI.xlsx
Figshare·2023Open Access
Linsenmeier_hnRNPA1-interface_SourceData_SI.xlsx
Figshare·2023Open Access
Supporting Information - interface-promoted liquid-amyloid transition of hnRNPA1 condensates
Figshare·2023Open Access
Linsenmeier_hnRNPA1-interface_SourceData_SI.xlsx
Figshare·2023Open Access
Linsenmeier_hnRNPA1-interface_SourceData_main.xlsx
Figshare·2023Open Access
Dynamic arrest and aging of biomolecular condensates are modulated by low-complexity domains, RNA and biochemical activity
Nature Communications·2022· 93 citedOpen Access
The interface of condensates of the hnRNPA1 low complexity domain promotes formation of amyloid fibrils
2022· 28 citedOpen Access
A conserved mechanism regulates reversible amyloids <i>via</i> pH-sensing regions
2022· 1 citedOpen Access
A Conserved Mechanism Regulates Reversible Amyloids &lt;i&gt;via&lt;/i&gt; pH-Sensing Regions
SSRN Electronic Journal·2022Open Access
Programmable Zwitterionic Droplets as Biomolecular Sorters and Model of Membraneless Organelles (Adv. Mater. 4/2022)
Advanced Materials·2022
Programmable Zwitterionic Droplets as Biomolecular Sorters and Model of Membraneless Organelles
Advanced Materials·2021· 47 cited
Programmable zwitterionic droplets as biomolecular sorters and model of membraneless organelles
2021· 6 citedOpen Access
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Frequent Co-authors

Paolo Arosio(25), Umberto Capasso Palmiero(12), Maria Hondele(10), Karsten Weis(10), Marie R. G. Kopp(10), Andreas M. Küffner(9), Fulvio Grigolato(7), Jiangtao Zhou(6), Raffaele Mezzenga(6), James Shorter(6), Lenka Faltova(5), Dany Liu(4), Dominik Zürcher(4), Carolina Paganini(4), Charlotte Seiffert(3), Dorothea Pinotsi(3), Leonidas Emmanoulidis(3), Ruchika Sachdev(3), Pascal Vallotton(3), Christopher F Mugler(3)