Kyohei Arita

Tokyo University of Science — Japan

Biochemistry, Genetics and Molecular Biology · Life Sciences

25h-index4.2kcitations94works2.92yr avg
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Research Topics

Epigenetics and DNA Methylation(40), RNA modifications and cancer(28), Cancer-related gene regulation(20), Ubiquitin and proteasome pathways(15), Genetics and Neurodevelopmental Disorders(13)

Publications94 total

Structural basis for E3 ubiquitin ligase UHRF1 binding to nucleosome core particle and histone H3 ubiquitination
Journal of Biological Chemistry·2025Open Access
Cryo-EM reveals evolutionarily conserved and distinct structural features of plant CG maintenance methyltransferase MET1
Nature Communications·2025· 2 citedOpen Access
Structures of USP7 in active and inactive states bound to DNMT1 revealed by cryo-EM
Structure·2025· 1 cited
Pain-stimulated ultrasound vocalizations and their impact on pain response in mice
PLoS ONE·2025Open Access
Pain-stimulated ultrasound vocalizations and their impact on pain response in mice
2025Open Access
Characterization of the Swi6/ <scp>HP1</scp> binding motif in its partner protein reveals the basis for the functional divergence of the <scp>HP1</scp> family proteins in fission yeast
The FASEB Journal·2025· 2 citedOpen Access
Computational Identification of Specific Genes and Those Functions on the Gut Microbiota
Preprints.org·2025· 1 citedOpen Access
A comprehensive review of structural insights into DNA methylation maintenance
Genes & Genetic Systems·2025Open Access
Development of peptide-based inhibitors against β-catenin using in silico approach
2024Open Access
CDCA7 is an evolutionarily conserved hemimethylated DNA sensor in eukaryotes
Science Advances·2024· 25 citedOpen Access
Structure of human DPPA3 bound to the UHRF1 PHD finger reveals its functional and structural differences from mouse DPPA3
Communications Biology·2024· 5 citedOpen Access
Cryo-electron microscopy reveals the impact of the nucleosome dynamics on transcription activity
The Journal of Biochemistry·2024· 1 citedOpen Access
Structure of human DPPA3 bound to the UHRF1 PHD finger reveals its functional and structural differences from mouse DPPA3
2024· 1 citedOpen Access
CDCA7 is a hemimethylated DNA adaptor for the nucleosome remodeler HELLS
2023· 2 citedOpen Access
Cooperative DNA-binding activities of Chp2 are critical for its function in heterochromatin assembly
The Journal of Biochemistry·2023· 3 cited
The termination of UHRF1-dependent PAF15 ubiquitin signaling is regulated by USP7 and ATAD5
eLife·2023· 15 citedOpen Access
Review for "&lt;scp&gt;ZBTB7A&lt;/scp&gt; regulates primed‐to‐naïve transition of pluripotent stem cells via recognition of the &lt;scp&gt;PNT&lt;/scp&gt; ‐associated sequence by Zinc Fingers 1–2 and recognition of γ‐globin −200 gene element by Zinc Fingers 1–4"
2023
Novel compound heterozygous mutations in <i>UHRF1</i> are associated with atypical immunodeficiency, centromeric instability and facial anomalies syndrome with distinctive genome-wide DNA hypomethylation
Human Molecular Genetics·2022· 24 cited
Structural basis for activation of DNMT1
Nature Communications·2022· 73 citedOpen Access
Structural basis for the unique multifaceted interaction of DPPA3 with the UHRF1 PHD finger
Nucleic Acids Research·2022· 19 citedOpen Access
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Frequent Co-authors

Masahiro Shirakawa(15), Atsuya Nishiyama(13), Makoto Nakanishi(13), Mariko Ariyoshi(12), Mamoru Sato(9), Hidehito Tochio(8), Satomi Kori(8), Yoshie Chiba(8), Toshiyuki Shimizu(7), Hiroshi Hashimoto(6), Junji Otani(5), Isao Suetake(5), Motoko Unoki(4), Toru Kawakami(4), Hironobu Hojo(4), Keiji Tanaka(4), Heinrich Leonhardt(4), Pierre‐Antoine Defossez(4), Amika Kikuchi(4), Michiyuki Yamada(3)