Keith E. Szulwach

Alameda Hospital — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

26h-index7.5kcitations34works0.02yr avg
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Research Topics

Epigenetics and DNA Methylation(24), MicroRNA in disease regulation(9), RNA modifications and cancer(9), Cancer-related gene regulation(9), Genetics and Neurodevelopmental Disorders(8)

Publications34 total

Engineered Allosteric Control Enhances Specificity and Potency of CRISPR-CasX-based Epigenetic Repressors
2026
Structural dynamics control the MicroRNA maturation pathway
Nucleic Acids Research·2016· 24 citedOpen Access
Eukaryotic Single-Cell DNA Sequencing
2016
Single-Cell Genetic Analysis Using Automated Microfluidics to Resolve Somatic Mosaicism
PLoS ONE·2015· 47 citedOpen Access
Abstract LB-129: Identifying tumor subpopulations and the functional consequences of intratumor heterogeneity using single-cell profiling of breast cancer patient-derived xenografts
Cancer Research·2015
Role of Tet1 and 5-hydroxymethylcytosine in cocaine action
Nature Neuroscience·2015· 184 citedOpen Access
Base-resolution methylation patterns accurately predict transcription factor bindings in vivo
Nucleic Acids Research·2015· 47 citedOpen Access
AGO3 Slicer activity regulates mitochondria–nuage localization of Armitage and piRNA amplification
The Journal of Cell Biology·2014· 66 citedOpen Access
Regulation of DNA methylation turnover at LTR retrotransposons and imprinted loci by the histone methyltransferase Setdb1
Proceedings of the National Academy of Sciences·2014· 115 citedOpen Access
Genome-wide antagonism between 5-hydroxymethylcytosine and DNA methylation in the adult mouse brain
Frontiers in Biology·2014· 27 citedOpen Access
Integrating DNA methylation dynamics into a framework for understanding epigenetic codes
BioEssays·2013· 49 citedOpen Access
U1 small nuclear ribonucleoprotein complex and RNA splicing alterations in Alzheimer’s disease
Proceedings of the National Academy of Sciences·2013· 335 citedOpen Access
<i>TET1</i> plays an essential oncogenic role in <i>MLL</i> -rearranged leukemia
Proceedings of the National Academy of Sciences·2013· 221 citedOpen Access
Chemical Modification-Assisted Bisulfite Sequencing (CAB-Seq) for 5-Carboxylcytosine Detection in DNA
Journal of the American Chemical Society·2013· 120 citedOpen Access
Subtelomeric hotspots of aberrant 5-hydroxymethylcytosine-mediated epigenetic modifications during reprogramming to pluripotency
Nature Cell Biology·2013· 93 citedOpen Access
Genome-wide Profiling of 5-Formylcytosine Reveals Its Roles in Epigenetic Priming
Cell·2013· 540 citedOpen Access
Tet-mediated covalent labelling of 5-methylcytosine for its genome-wide detection and sequencing
Nature Communications·2013· 50 citedOpen Access
Tet-assisted bisulfite sequencing of 5-hydroxymethylcytosine
Nature Protocols·2012· 258 citedOpen Access
Sjögren Syndrome Antigen B (SSB)/La Promotes Global MicroRNA Expression by Binding MicroRNA Precursors through Stem-Loop Recognition
Journal of Biological Chemistry·2012· 68 citedOpen Access
Genome-wide DNA hydroxymethylation changes are associated with neurodevelopmental genes in the developing human cerebellum
Human Molecular Genetics·2012· 183 citedOpen Access
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Frequent Co-authors

Peng Jin(29), Chuan He(13), Chun‐Xiao Song(12), Xuekun Li(10), Yujing Li(10), Hao Wu(6), Xinyu Zhao(6), Qing Dai(5), Bing Ren(5), Craig Street(4), Yuping Luo(4), Gary C. Hon(3), Li Lin(3), Richard D. Smrt(3), Wen‐Di Li(3), Weixiang Guo(3), Junmin Peng(3), Miao Yu(3), Ranhui Duan(3), Ye Fu(2)