Stefan Pflanz

Gilead Sciences (United States) — United States

Medicine · Health Sciences

28h-index7.9kcitations70works0.02yr avg
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Research Topics

Cytokine Signaling Pathways and Interactions(16), Hepatitis B Virus Studies(13), Hepatitis C virus research(12), Monoclonal and Polyclonal Antibodies Research(10), Immune Cell Function and Interaction(10)

Publications70 total

Effects of Hepatitis B Surface Antigen on Virus-Specific and Global T Cells in Patients With Chronic Hepatitis B Virus infection
Gastroenterology·2020· 180 citedOpen Access
Identification of NK Cell Subpopulations That Differentiate HIV-Infected Subject Cohorts with Diverse Levels of Virus Control
Journal of Virology·2019· 55 citedOpen Access
Differential Serum Cytokine Profiles in Patients with Chronic Hepatitis B, C, and Hepatocellular Carcinoma
Scientific Reports·2017· 58 citedOpen Access
Soluble intercellular adhesion molecule-1 is associated with hepatocellular carcinoma risk: multiplex analysis of serum markers
Scientific Reports·2017· 18 citedOpen Access
In vitro and in vivo characterization of the selective toll-like receptor 8 agonist GS-9688
Journal of Hepatology·2017· 10 cited
Modifications of virus-specific and total B cell populations by hepatitis B virus infection
Journal of Hepatology·2017
Antibody‐dependent and antibody‐independent uptake of HBsAg across human leucocyte subsets is similar between individuals with chronic hepatitis B virus infection and healthy donors
Journal of Viral Hepatitis·2016· 14 cited
812 High Serum Soluble Intercellular Adhesion Molecule 1 (sICAM-1) Concentration Is Associated With Hepatocellular Carcinoma Development in Hepatitis B Virus, Hepatitis C Virus, and Non-Viral Liver Disease: Multiplex Analysis of 51 Cytokines and Other Serum Markers
Gastroenterology·2016
Mo1517 Differential Cytokine Profiles in Patients With Hepatocellular Carcinoma Related to Hepatitis B Virus (HBV) and Hepatitis C Virus (HCV) Infection
Gastroenterology·2016
Molecular Determinants of GS-9620-Dependent TLR7 Activation
PLoS ONE·2016· 19 citedOpen Access
High Serum Soluble Intercellular Adhesion Molecule 1 (ICAM-1) Concentration Is Associated with Hepatocellular Carcinoma (HCC) Development in HBV, HCV, and Non-Viral Liver Disease: Multiplex Analysis of 51 Cytokines and Other Serum Markers
Journal of Hepatology·2016· 1 cited
Differential Cytokine Profiles in Patients with Hepatocellular Carcinoma Related to Hepatitis B Virus and Hepatitis C Virus Infection
Journal of Hepatology·2016
Application of Mass Cytometry Time of Flight (CYTOF) for Systematic Characterization of PBMC Phenotypes Associated with HBSAG Serum Levels in Chronic HBV Patients
Journal of Hepatology·2016
P0574 : A signature of elevated immune activation is observed in the peripheral blood of virally suppressed, HBeAg-negative chronic HBV patients
Journal of Hepatology·2015
P0645 : Non-synonymous single-nucleotide polymorphisms (SNPs) in TLR7 do not impact GS-9620 dependent TLR7 activation
Journal of Hepatology·2015
Epidermal Expression and Regulation of Interleukin-33 during Homeostasis and Inflammation: Strong Species Differences
Journal of Investigative Dermatology·2015· 62 citedOpen Access
The oral toll-like receptor-7 agonist GS-9620 in patients with chronic hepatitis B virus infection
Journal of Hepatology·2015· 183 cited
Safety, Pharmacokinetics and Pharmacodynamics of the Oral Toll-Like Receptor 7 Agonist GS-9620 in Treatment-Naive Patients with Chronic Hepatitis C
Antiviral Therapy·2014· 30 cited
P1052 DETERMINANTS OF VARIABILITY IN ISG15 GENE EXPRESSION IN PATIENTS WITH CHRONIC HEPATITIS B (CHB) INFECTION DURING TREATMENT WITH ORAL TLR7 AGONIST GS-9620
Journal of Hepatology·2014
Pharmacokinetic and Pharmacodynamic Properties of GS-9620, a Novel Toll-Like Receptor 7 Agonist, Demonstrate Interferon-Stimulated Gene Induction without Detectable Serum Interferon at Low Oral Doses
Journal of Pharmacology and Experimental Therapeutics·2013· 67 cited
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Frequent Co-authors

Peter C. Heinrich(9), Gerhard Müller‐Newen(8), Joachim Grötzinger(7), Robert A. Kastelein(6), Terrill K. McClanahan(5), René de Waal Malefyt(5), Jörg Volkland(5), Patrick A. Baeuerle(5), Anuj Gaggar(5), Andrew L. Rankin(4), John S. Lumsden(4), Peter Kufer(4), Tobias Raum(4), Ingo Kurth(4), Mindie H. Nguyen(4), Linda Hibbert(3), Elena Vaisberg(3), Daniel M. Gorman(3), Patricia Bourne(3), Rob Kastelein(3)