Johanna Chiffelle

Ludwig Cancer Research — Switzerland

Medicine · Health Sciences

13h-index975citations23works42.02yr avg
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Research Topics

CAR-T cell therapy research(14), Immunotherapy and Immune Responses(12), vaccines and immunoinformatics approaches(6), Cancer Immunotherapy and Biomarkers(5), T-cell and B-cell Immunology(4)

Publications23 total

Applications of T-cell receptor specificity annotation models for quality control and immunomonitoring in adoptive T-cell therapies
2026Open Access
A comprehensive proteogenomic pipeline for neoantigen discovery to advance personalized cancer immunotherapy
Nature Biotechnology·2024· 65 citedOpen Access
Tumor-reactive T cell clonotype dynamics underlying clinical response to TIL therapy in melanoma
Immunity·2024· 36 cited
Predicting Antigen‐Specificities of Orphan T Cell Receptors from Cancer Patients with TCRpcDist
Advanced Science·2024· 6 citedOpen Access
Author Correction: Identification of clinically relevant T cell receptors for personalized T cell therapy using combinatorial algorithms
Nature Biotechnology·2024· 4 citedOpen Access
Personalized cancer T-cell therapy takes the stage, mirroring vaccine success
The Journal of Experimental Medicine·2024· 3 citedOpen Access
Identification of clinically relevant T cell receptors for personalized T cell therapy using combinatorial algorithms
Nature Biotechnology·2024· 28 citedOpen Access
PGE2 inhibits TIL expansion by disrupting IL-2 signalling and mitochondrial function
Nature·2024· 164 citedOpen Access
Response to tumor-infiltrating lymphocyte adoptive therapy is associated with preexisting CD8 <sup>+</sup> T-myeloid cell networks in melanoma
Science Immunology·2024· 72 citedOpen Access
Machine learning methods and harmonized datasets improve immunogenic neoantigen prediction
Immunity·2023· 77 citedOpen Access
Tumor-reactive clonotype dynamics underlying clinical response to TIL therapy in melanoma
2023· 8 citedOpen Access
TCRpcDist: Estimating TCR physico-chemical similarity to analyze repertoires and predict specificities
2023· 4 citedOpen Access
Neoantigen-specific CD8 T cells with high structural avidity preferentially reside in and eliminate tumors
Nature Communications·2023· 63 citedOpen Access
TCR sequencing and cloning methods for repertoire analysis and isolation of tumor-reactive TCRs
Cell Reports Methods·2023· 45 citedOpen Access
Tumor Microenvironment Cellular Crosstalk Predicts Response to Adoptive TIL Therapy in Melanoma
2022· 5 citedOpen Access
Sensitive identification of neoantigens and cognate TCRs in human solid tumors
Nature Biotechnology·2021· 95 citedOpen Access
The Promise of Personalized TCR-Based Cellular Immunotherapy for Cancer Patients
Frontiers in Immunology·2021· 11 citedOpen Access
In-depth immune and molecular profiling of melanoma patients receiving adoptive T-cell therapy reveals biomarkers of efficacy in ATATIL study.
Journal of Clinical Oncology·2021· 1 cited
Author Correction: Personalized cancer vaccine strategy elicits polyfunctional T cells and demonstrates clinical benefits in ovarian cancer
npj Vaccines·2021· 4 citedOpen Access
Personalized cancer vaccine strategy elicits polyfunctional T cells and demonstrates clinical benefits in ovarian cancer
npj Vaccines·2021· 47 citedOpen Access
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Frequent Co-authors

Alexandre Harari(21), George Coukos(18), Lana E. Kandalaft(15), Michal Bassani‐Sternberg(15), Sara Bobisse(14), Marion Arnaud(13), Denarda Dangaj Laniti(11), David Barras(10), Raphaël Genolet(8), Marta A. S. Perez(8), Vincent Zoete(8), Florian Huber(8), Fabrizio Benedetti(7), Julien Schmidt(7), Rémy Pétremand(7), Eleonora Ghisoni(6), Isaac Crespo(6), Blanca Navarro Rodrigo(6), Brian J. Stevenson(6), Aymeric Auger(6)