L. Mazzarella

Sapienza University of Rome — Italy

Biochemistry, Genetics and Molecular Biology · Life Sciences

44h-index6.2kcitations259works5.02yr avg
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Research Topics

Protein Structure and Dynamics(59), Hemoglobin structure and function(59), Enzyme Structure and Function(51), Marine Sponges and Natural Products(28), Chemical Synthesis and Analysis(24)

Publications259 total

Platelets tune fear memory in mice
Cell Reports·2025· 4 citedOpen Access
Time-dependent phenotypical changes of microglia drive alterations in hippocampal synaptic transmission in acute slices
Frontiers in Cellular Neuroscience·2024· 6 citedOpen Access
The structural features of an ancient ribonuclease from Salmo salar reveal an intriguing case of auto-inhibition
International Journal of Biological Macromolecules·2021· 3 cited
The unique structural features of carbonmonoxy hemoglobin from the sub-Antarctic fish Eleginops maclovinus
Scientific Reports·2019· 3 citedOpen Access
Crystal structure of monocarboxylated hemoglobin from the sub-Antarctic fish Eleginops maclovinus
2019· 3 citedOpen Access
Crystal structure of the ferric homotetrameric β 4 human hemoglobin
Biophysical Chemistry·2018· 4 cited
THE X-RAY STRUCTURE OF FERRIC-BETA4 HUMAN HEMOGLOBIN
2018
Fine Sampling of the R→T Quaternary‐Structure Transition of a Tetrameric Hemoglobin
Chemistry - A European Journal·2016· 8 cited
A regular thymine tetrad and a peculiar supramolecular assembly in the first crystal structure of an all-LNA G-quadruplex
Acta Crystallographica Section D Biological Crystallography·2014· 12 cited
Structural modifications induced by the switch from an endogenous bis-histidyl to an exogenous cyanomet hexa-coordination in a tetrameric haemoglobin
RSC Advances·2014· 2 cited
Duplex–quadruplex motifs in a peculiar structural organization cooperatively contribute to thrombin binding of a DNA aptamer
Acta Crystallographica Section D Biological Crystallography·2013· 96 cited
Three-dimensional domain swapping and supramolecular protein assembly: insights from the X-ray structure of a dimeric swapped variant of human pancreatic RNase
Acta Crystallographica Section D Biological Crystallography·2013· 16 cited
The structure of the CD3 ζζ transmembrane dimer in POPC and raft-like lipid bilayer: A molecular dynamics study
Biochimica et Biophysica Acta (BBA) - Biomembranes·2013· 9 cited
The X-ray crystal structure of a dimeric variant of human pancreatic ribonuclease
2013
A novel interdomain interface in crystallins: structural characterization of the βγ-crystallin from<i>Geodia cydonium</i>at 0.99 Å resolution
Acta Crystallographica Section D Biological Crystallography·2013· 6 cited
Role of tertiary structures on the Root effect in fish hemoglobins
Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics·2013· 9 cited
Crystal structure of T-state carbonmonoxy hemoglobin from Trematomus bernacchii at pH 8.4
2013
Selective X-ray-induced NO photodissociation in haemoglobin crystals: evidence from a Raman-assisted crystallographic study
Acta Crystallographica Section D Biological Crystallography·2012· 15 citedOpen Access
Crystal Structure of Human Alpha Thrombin in Complex with a 27-mer Aptamer Bound to Exosite II
2012
ATP regulation of the ligand-binding properties in temperate and cold-adapted haemoglobins. X-ray structure and ligand-binding kinetics in the sub-Antarctic fish <i>Eleginops maclovinus</i>
Molecular BioSystems·2012· 12 cited
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Frequent Co-authors

Adriana Zagari(25), Luigi Vitagliano(23), Antonello Merlino(14), Filomena Sica(14), Sante Capasso(9), Rita Berisio(8), Guido di Prisco(7), Carlo Andrea Mattia(6), Luciana Esposito(5), Alessandro Vergara(5), Alberto Di Donato(4), Giovanna Bonomi(4), Cinzia Verde(4), Irene Russo Krauss(3), Giuseppe Cimino(3), R. Puliti(3), Marc A. Ceruso(3), Antonio Randazzo(2), M. F. Perutz(2), Hilary Muirhead(2)