Ruthiran Kugathasan

Imperial College London — United Kingdom

Medicine · Health Sciences

11h-index2.1kcitations17works0.02yr avg
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Research Topics

SARS-CoV-2 and COVID-19 Research(12), Respiratory viral infections research(6), Animal Virus Infections Studies(5), SARS-CoV-2 detection and testing(5), Viral gastroenteritis research and epidemiology(4)

Publications17 total

Omicron breakthrough infections in vaccinated or previously infected hamsters
Proceedings of the National Academy of Sciences·2023· 10 citedOpen Access
Deep mutagenesis scanning using whole trimeric SARS-CoV-2 spike highlights the importance of NTD-RBD interactions in determining spike phenotype
PLoS Pathogens·2023· 15 citedOpen Access
A self-amplifying RNA vaccine protects against SARS-CoV-2 (D614G) and Alpha variant of concern (B.1.1.7) in a transmission-challenge hamster model
Vaccine·2022· 12 citedOpen Access
Mutations that adapt SARS-CoV-2 to mink or ferret do not increase fitness in the human airway
Cell Reports·2022· 68 citedOpen Access
The altered entry pathway and antigenic distance of the SARS-CoV-2 Omicron variant map to separate domains of spike protein
2022· 291 citedOpen Access
Polymer formulated self-amplifying RNA vaccine is partially protective against influenza virus infection in ferrets
Oxford Open Immunology·2022· 10 citedOpen Access
Mutations that adapt SARS-CoV-2 to mustelid hosts do not increase fitness in the human airway.
Research Square (Research Square)·2021· 3 citedOpen Access
Mutations that adapt SARS-CoV-2 to mustelid hosts do not increase fitness in the human airway
2021· 3 citedOpen Access
The furin cleavage site in the SARS-CoV-2 spike protein is required for transmission in ferrets
Nature Microbiology·2021· 785 citedOpen Access
Viral Infectivity in Patients Undergoing Tracheotomy With COVID‐19: A Preliminary Study
Otolaryngology·2021· 1 citedOpen Access
SARS-CoV-2 lateral flow assays for possible use in national covid-19 seroprevalence surveys (React 2): diagnostic accuracy study
BMJ·2021· 79 citedOpen Access
Increased transmission of SARS-CoV-2 lineage B.1.1.7 (VOC 2020212/01) is not accounted for by a replicative advantage in primary airway cells or antibody escape
2021· 96 cited
The furin cleavage site of SARS-CoV-2 spike protein is a key determinant for transmission due to enhanced replication in airway cells
2020· 103 citedOpen Access
Clinical and laboratory evaluation of SARS-CoV-2 lateral flow assays for use in a national COVID-19 seroprevalence survey
Thorax·2020· 155 citedOpen Access
The Consequences of Egg Adaptation in the H3N2 Component to the Immunogenicity of Live Attenuated Influenza Vaccine
2019Open Access
HIV-1 drug resistance before initiation or re-initiation of first-line antiretroviral therapy in low-income and middle-income countries: a systematic review and meta-regression analysis
The Lancet Infectious Diseases·2017· 408 citedOpen Access
Diffuse White Matter Signal Abnormalities on Magnetic Resonance Imaging Are Associated With Human Immunodeficiency Virus Type 1 Viral Escape in the Central Nervous System Among Patients With Neurological Symptoms
Clinical Infectious Diseases·2017· 42 citedOpen Access

Frequent Co-authors

William Barclay(15), Jonathan C. Brown(12), Jie Zhou(11), Rebecca Frise(11), Thomas P. Peacock(9), Laury Baillon(8), Daniel H. Goldhill(7), Paul F. McKay(7), Maya Moshe(6), Robin J. Shattock(5), Rebecca Penn(4), Nazia Thakur(4), Wilhelm Furnon(4), Giuditta De Lorenzo(4), Vanessa M. Cowton(4), Jessica L. Quantrill(4), Arvind H. Patel(4), Massimo Palmarini(4), Dalan Bailey(4), Jack A. Hassard(3)