Morten Hentzer

Lundbeck (Denmark) — Denmark

Biochemistry, Genetics and Molecular Biology · Life Sciences

38h-index14.4kcitations61works0.02yr avg
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Research Topics

Bacterial biofilms and quorum sensing(42), Antibiotic Resistance in Bacteria(12), Cystic Fibrosis Research Advances(10), Antimicrobial Peptides and Activities(9), Bacterial Genetics and Biotechnology(8)

Publications61 total

Development of 18F/11C-Labeled Pyrrolo-Pyridine/Pyrimidine LRRK2 Selective PET Radioligands
Pharmaceuticals·2025Open Access
Investigational Studies on Imaging CSF-1 Receptors in the Brain
Nuclear Medicine and Biology·2025
Erratum for Danhorn et al., “Phosphorus Limitation Enhances Biofilm Formation of the Plant Pathogen <i>Agrobacterium tumefaciens</i> through the PhoR-PhoB Regulatory System”
Journal of Bacteriology·2024Open Access
Design and Synthesis of Pyrrolo[2,3-<i>d</i>]pyrimidine-Derived Leucine-Rich Repeat Kinase 2 (LRRK2) Inhibitors Using a Checkpoint Kinase 1 (CHK1)-Derived Crystallographic Surrogate
Journal of Medicinal Chemistry·2021· 36 citedOpen Access
Animal models of chronic and recurrent <i>Pseudomonas aeruginosa</i> lung infection: significance of macrolide treatment
Apmis·2021· 10 cited
LRRK2 exonic variants associated with Parkinson’s disease augment phosphorylation levels for LRRK2-Ser1292 and Rab10-Thr73
2018· 15 citedOpen Access
Design of Leucine-Rich Repeat Kinase 2 (LRRK2) Inhibitors Using a Crystallographic Surrogate Derived from Checkpoint Kinase 1 (CHK1)
Journal of Medicinal Chemistry·2017· 47 citedOpen Access
The design and SAR of a novel series of 2-aminopyridine based LRRK2 inhibitors
Bioorganic & Medicinal Chemistry Letters·2017· 16 citedOpen Access
Protection of Primary Dopaminergic Midbrain Neurons by GPR139 Agonists Supports Different Mechanisms of MPP+ and Rotenone Toxicity
Frontiers in Cellular Neuroscience·2016· 19 citedOpen Access
High-throughput screening of antagonists for the orphan G-protein coupled receptor GPR139
Acta Pharmacologica Sinica·2015· 34 citedOpen Access
Brexpiprazole I: In Vitro and In Vivo Characterization of a Novel Serotonin-Dopamine Activity Modulator
Journal of Pharmacology and Experimental Therapeutics·2014· 347 cited
Abnormal visual gain control in a Parkinson's disease model
Human Molecular Genetics·2014· 50 citedOpen Access
PhoR-PhoB Regulatory System through the Agrobacterium tumefaciens Formation of the Plant Pathogen Phosphorus Limitation Enhances Biofilm
2014
P.2.b.008 In vitro effects of the multimodal antidepressant Lu AA21004 at human and rat 5-HT1A, 5-HT1B, 5-HT3 and 5-HT7 receptors, and 5-HT transporters
European Neuropsychopharmacology·2012· 7 cited
Hit-to-lead investigation of a series of novel combined dopamine D2 and muscarinic M1 receptor ligands with putative antipsychotic and pro-cognitive potential
Bioorganic & Medicinal Chemistry Letters·2012· 9 citedOpen Access
Fluorescence-Based Reporter for Gauging Cyclic Di-GMP Levels in Pseudomonas aeruginosa
Applied and Environmental Microbiology·2012· 290 citedOpen Access
Discovery and SAR of a Series of Agonists at Orphan G Protein-Coupled Receptor 139
ACS Medicinal Chemistry Letters·2011· 49 cited
Discovery of<i>N</i>-{1-[3-(3-Oxo-2,3-dihydrobenzo[1,4]oxazin-4-yl)propyl]piperidin-4-yl}-2-phenylacetamide (Lu AE51090): An Allosteric Muscarinic M<sub>1</sub>Receptor Agonist with Unprecedented Selectivity and Procognitive Potential
Journal of Medicinal Chemistry·2010· 37 citedOpen Access
Quorum Sensing Regulation in Aeromonas hydrophila
Journal of Molecular Biology·2010· 41 cited
Discovery of a potent and brain penetrant mGluR5 positive allosteric modulator
Bioorganic & Medicinal Chemistry Letters·2009· 27 citedOpen Access
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Frequent Co-authors

Michael Givskov(36), Niels Høiby(13), Søren Molin(12), Leo Eberl(12), Arne Heydorn(8), Matthew R. Parsek(8), Thomas Bjarnsholt(7), Garrick P. Smith(7), Jens Bo Andersen(6), Thomas Bovbjerg Rasmussen(5), Peter Østrup Jensen(5), Oana Ciofu(5), Kenneth Vielsted Christensen(5), Katharina Riedel(4), D.S. Williamson(4), Bjarne Kjær Ersbøll(3), Staffan Kjelleberg(3), John Nielsen(3), Claus Moser(3), Christoffer Bundgaard(3)