Simon Wing Fai Mok

Macau University of Science and Technology — MO

Medicine · Health Sciences

23h-index1.4kcitations43works22.02yr avg
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Research Topics

Autophagy in Disease and Therapy(8), Prion Diseases and Protein Misfolding(6), Epigenetics and DNA Methylation(5), Histone Deacetylase Inhibitors Research(5), Ginseng Biological Effects and Applications(5)

Publications43 total

Sirt7 protects against vascular calcification via modulation of reactive oxygen species and senescence of vascular smooth muscle cells
Free Radical Biology and Medicine·2024· 11 citedOpen Access
Modulation of alveolar macrophage and mitochondrial fitness by medicinal plant-derived nanovesicles to mitigate acute lung injury and viral pneumonia
Journal of Nanobiotechnology·2024· 33 citedOpen Access
<scp>PFKFB3</scp> ‐driven vascular smooth muscle cell glycolysis promotes vascular calcification via the altered <scp>FoxO3</scp> and lactate production
The FASEB Journal·2023· 14 citedOpen Access
The potential development of drug resistance in rheumatoid arthritis patients identified with p53 mutations
Genes & Diseases·2023· 7 citedOpen Access
<i>N</i>-Acetylcysteine overcomes epalrestat-mediated increase of toxic 4-hydroxy-2-nonenal and potentiates the anti-arthritic effect of epalrestat in AIA model
International Journal of Biological Sciences·2023· 10 citedOpen Access
The short-chain fatty acid butyrate accelerates vascular calcification via regulation of histone deacetylases and NF-κB signaling
Vascular Pharmacology·2022· 50 cited
AGEs-Induced Calcification and Apoptosis in Human Vascular Smooth Muscle Cells Is Reversed by Inhibition of Autophagy
Frontiers in Pharmacology·2021· 13 citedOpen Access
Saponins isolated from Radix polygalae extent lifespan by modulating complement C3 and gut microbiota
Pharmacological Research·2021· 26 cited
Novel ginsenoside derivative 20(S)-Rh2E2 suppresses tumor growth and metastasis in vivo and in vitro via intervention of cancer cell energy metabolism
Cell Death and Disease·2020· 18 citedOpen Access
SERCA and P-glycoprotein inhibition and ATP depletion are necessary for celastrol-induced autophagic cell death and collateral sensitivity in multidrug-resistant tumor cells
Pharmacological Research·2020· 46 cited
HM30181A, a potent P-glycoprotein inhibitor, potentiates the absorption and &lt;i&gt;in vivo&lt;/i&gt; antitumor efficacy of paclitaxel in an orthotopic brain tumor model
Cancer Biology and Medicine·2020· 14 citedOpen Access
Neferine induces autophagy-dependent cell death in apoptosis-resistant cancers via ryanodine receptor and Ca2+-dependent mechanism
Scientific Reports·2019· 53 citedOpen Access
Neferine induces autophagy-dependent cell death in apoptosis-resistant cancers via ryanodine receptor and Ca 2+ -dependent mechanism
2019
A Novel Drug Resistance Mechanism: Genetic Loss of Xeroderma Pigmentosum Complementation Group C (XPC) Enhances Glycolysis-Mediated Drug Resistance in DLD-1 Colon Cancer Cells
Frontiers in Pharmacology·2019· 10 citedOpen Access
Ca<sup>2+</sup> signalling plays a role in celastrol‐mediated suppression of synovial fibroblasts of rheumatoid arthritis patients and experimental arthritis in rats
British Journal of Pharmacology·2019· 84 citedOpen Access
Novel dauricine derivatives suppress cancer via autophagy-dependent cell death
Bioorganic Chemistry·2018· 20 citedOpen Access
Corrigendum: Novel Peroxides as Promising Anticancer Agents with Unexpected Depressed Antimalarial Activity
ChemMedChem·2018· 3 citedOpen Access
Innenrücktitelbild: Selective Inhibition of Lysine‐Specific Demethylase 5A (KDM5A) Using a Rhodium(III) Complex for Triple‐Negative Breast Cancer Therapy (Angew. Chem. 40/2018)
Angewandte Chemie·2018Open Access
Inside Back Cover: Selective Inhibition of Lysine‐Specific Demethylase 5A (KDM5A) Using a Rhodium(III) Complex for Triple‐Negative Breast Cancer Therapy (Angew. Chem. Int. Ed. 40/2018)
Angewandte Chemie International Edition·2018· 3 citedOpen Access
A Method for Rapid Screening of Anilide-Containing AMPK Modulators Based on Computational Docking and Biological Validation
Frontiers in Pharmacology·2018· 10 citedOpen Access
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Frequent Co-authors

Vincent Kam Wai Wong(32), Betty Yuen Kwan Law(27), Yuan Qing Qu(10), Su Xu(9), Jianming Wu(8), Liang Liu(8), Ivo Ricardo de Seabra Rodrigues Dias(7), Anguo Wu(7), Paolo Coghi(7), Dik‐Lung Ma(6), Chung‐Hang Leung(6), Yu Han(6), Wanhe Wang(5), Hai‐Jing Zhong(5), Flora Gordillo-Martínez(5), Guan‐Jun Yang(4), Wu Chun(4), Xiangmin Miao(4), Ke‐Jia Wu(4), Chun‐Yuen Wong(4)