Hideyuki Okano

Jikei University School of Medicine — Japan

Biochemistry, Genetics and Molecular Biology · Life Sciences

143h-index85.0kcitations1.8kworks3.32yr avg
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Research Topics

Pluripotent Stem Cells Research(356), Neurogenesis and neuroplasticity mechanisms(309), Nerve injury and regeneration(151), CRISPR and Genetic Engineering(138), RNA Research and Splicing(124)

Publications1.8k total

Early pathogenesis of spinal and bulbar muscular atrophy uncovered by human iPSC-derived motor neurons highlights pathogenic neuropeptides as therapeutic targets
2025
An acyclic nucleic acid-modified siRNA targeting CAG expansions for polyglutamine disease treatment
Molecular Therapy — Nucleic Acids·2025· 1 citedOpen Access
A genome-wide association study identifies the GPM6A locus associated with age at onset in ALS
Communications Biology·2025Open Access
Correction: Generation of Human Melanocytes from Induced Pluripotent Stem Cells
PLoS ONE·2025Open Access
Selective agonism of GPR34 stimulates microglial uptake and clearance of amyloid β fibrils
Alzheimer s Research & Therapy·2025· 2 citedOpen Access
Visualization and quantification of facial muscles with 9.4T MRI-DTI in common marmosets ( <i>Callithrix jacchus</i> )
Royal Society Open Science·2025Open Access
Advancements in differentiation of induced pluripotent stem cells into specialized neuronal subtypes
Neural Regeneration Research·2025Open Access
Rescue of imprinted genes by epigenome editing in human cellular models of Prader-Willi syndrome
Nature Communications·2025· 2 citedOpen Access
Cerebrospinal fluid extracellular vesicle-derived miR-9-3p in spinal cord injury with neuroprotective implications and biomarker development
Communications Biology·2025· 1 citedOpen Access
Generation of a human iPSC line with EGFP knock-in at the ATRX locus for visualization of chromatin remodeler dynamics and nuclear condensate formation
Stem Cell Research·2025Open Access
Modeling Mitochondrial Disease Using Brain Organoids: A Focus on Mitochondrial Encephalomyopathy, Lactic Acidosis, and Stroke-like Episodes
Journal of Visualized Experiments·2025· 1 cited
Functional connectivity, structural connectivity, and inter-individual variability in Drosophila melanogaster
2025Open Access
Functional connectivity, structural connectivity, and inter-individual variability in Drosophila melanogaster
2025Open Access
Author response for "Visualisation and quantification of facial muscles with 9.4T MRI-DTI in common marmosets (Callithrix jacchus)"
2025
The effect of multichannel coils on the brain network of the common marmoset
Proceedings on CD-ROM - International Society for Magnetic Resonance in Medicine. Scientific Meeting and Exhibition/Proceedings of the International Society for Magnetic Resonance in Medicine, Scientific Meeting and Exhibition·2025
Comprehensive Analysis of Brain Connectivity and Optimal Sample Size in Common Marmosets Under Isoflurane Anesthesia
Proceedings on CD-ROM - International Society for Magnetic Resonance in Medicine. Scientific Meeting and Exhibition/Proceedings of the International Society for Magnetic Resonance in Medicine, Scientific Meeting and Exhibition·2025
Unveiling Brain Volume Patterns by Sex and Age in Marmosets
Proceedings on CD-ROM - International Society for Magnetic Resonance in Medicine. Scientific Meeting and Exhibition/Proceedings of the International Society for Magnetic Resonance in Medicine, Scientific Meeting and Exhibition·2025
Pathological changes in brain networks in P301S tau transgenic mouse model
Proceedings on CD-ROM - International Society for Magnetic Resonance in Medicine. Scientific Meeting and Exhibition/Proceedings of the International Society for Magnetic Resonance in Medicine, Scientific Meeting and Exhibition·2025
Investigation of water molecule metabolism in in vivo and ex vivo models using time-dependent diffusion MRI with long diffusion times
Proceedings on CD-ROM - International Society for Magnetic Resonance in Medicine. Scientific Meeting and Exhibition/Proceedings of the International Society for Magnetic Resonance in Medicine, Scientific Meeting and Exhibition·2025
The Brain/MINDS 3D Digital Marmoset Brain Atlas Version 2.0: Population-Based Cortical Parcellations With Multi-Modal Standard Templates
2025Open Access
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Frequent Co-authors

Yohei Okada(10), Masaya Nakamura(9), Shinsuke Shibata(8), Yoshiaki Toyama(6), Shinya Yamanaka(6), Takaki Miyata(6), Shin‐ichi Sakakibara(6), Takuya Shimazaki(5), Yumi Matsuzaki(5), Kazunobu Sawamoto(5), Takao Imai(5), Narihito Nagoshi(4), Masato Koike(4), Yasuo Uchiyama(4), Keiichi Fukuda(4), Osahiko Tsuji(4), Hiroyuki Katoh(3), Kyoko Miura(3), Masaharu Ogawa(3), Atsushi Miyawaki(3)