Edwin K. Silverman

Broad Institute — United States

Medicine · Health Sciences

135h-index68.5kcitations1.1kworks5.92yr avg
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Research Topics

Chronic Obstructive Pulmonary Disease (COPD) Research(595), Asthma and respiratory diseases(249), Respiratory Support and Mechanisms(139), Genetic Associations and Epidemiology(123), Neonatal Respiratory Health Research(94)

Publications983 total

Switch-like methylation of functional pathways distinguishes COPD and idiopathic pulmonary fibrosis
2025Open Access
Nasal epithelium and blood transcriptomic signatures associations with smoking and exacerbations
European Respiratory Journal·2025
Abstract 4363130: Multi-Omic Analyses Identifies Novel Candidate Molecular Drivers of Coronary Artery Calcification
Circulation·2025
Mosaic chromosomal alterations in blood across ancestries using whole-genome sequencing
UNC Libraries·2025Open Access
An optimized variant prioritization process for rare disease diagnostics: recommendations for Exomiser and Genomiser
Genome Medicine·2025· 5 citedOpen Access
Aberrant activation of TCL1A promotes stem cell expansion in clonal haematopoiesis
UNC Libraries·2025Open Access
Genetic architecture and analysis practices of circulating metabolites in the NHLBI Trans-Omics for Precision Medicine Program
The American Journal of Human Genetics·2025· 1 citedOpen Access
Diagnostic Approach for COPD—Reply
JAMA·2025
Race, Environmental Exposures, and Interstitial Lung Abnormalities
American Journal of Respiratory and Critical Care Medicine·2025
Visual and Quantitative Interstitial Lung Abnormality Progression in COPDGene
American Journal of Respiratory and Critical Care Medicine·2025· 2 citedOpen Access
How exposomic tools complement and enrich genomic research
Cell Genomics·2025· 4 citedOpen Access
Assessing inflammatory protein biomarkers in COPD subjects with and without alpha-1 antitrypsin deficiency
Respiratory Research·2025· 2 citedOpen Access
Proteomic discovery analysis of quantitatively assessed emphysema in the general population. The MESA Lung Study
Respiratory Research·2025Open Access
Frailty associates with respiratory exacerbations and mortality in the COPDGene cohort
Aging·2025· 3 citedOpen Access
Deep Learning of Suboptimal Spirometry to Predict Respiratory Outcomes and Mortality
2025· 1 citedOpen Access
Proteomic biomarkers of emphysema-predominant and non-emphysema-predominant chronic obstructive pulmonary disease
EBioMedicine·2025· 4 citedOpen Access
A Multidimensional Diagnostic Approach for Chronic Obstructive Pulmonary Disease
JAMA·2025· 13 citedOpen Access
Inherited causes of clonal haematopoiesis in 97,691 whole genomes
UNC Libraries·2025· 1 citedOpen Access
Author Correction: Inherited causes of clonal haematopoiesis in 97,691 whole genomes
UNC Libraries·2025Open Access
B-cell immune repertoire sequencing in tobacco cigarette smoking, vaping, and chronic obstructive pulmonary disease in the COPDGene cohort
Frontiers in Immunology·2025· 1 citedOpen Access
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Frequent Co-authors

James D. Crapo(18), Barry J. Make(17), John E. Hokanson(16), Terri H. Beaty(15), Per Bakke(15), David A. Lomas(14), Ruth Tal‐Singer(14), Jørgen Vestbo(14), Harvey O. Coxson(13), Scott T. Weiss(13), Elizabeth A. Regan(12), William MacNee(12), Michael H. Cho(12), Dawn L. DeMeo(12), Bartolomé R. Celli(11), Stephen I. Rennard(11), Àlvar Agustí(10), David A. Lynch(9), Peter M.A. Calverley(9), Lisa Edwards(9)