Maria Hatzoglou

Case Western Reserve University — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

54h-index10.6kcitations170works5.32yr avg
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Research Topics

Endoplasmic Reticulum Stress and Disease(42), RNA regulation and disease(37), RNA and protein synthesis mechanisms(36), RNA Research and Splicing(32), RNA modifications and cancer(28)

Publications170 total

rRNA Expansion Segments Mediate Ribosome Dimerization as a Conserved Stress Response
2026Open Access
eIF2B Selectively Anchors and Activates Mutant KRAS
2025
DDX3X acts as a selective dual switch regulator of mRNA translation in acute ER stress
Cell Reports·2025Open Access
Convergent activation of the integrated stress response and ER–mitochondria uncoupling in VAPB-associated ALS
EMBO Molecular Medicine·2025· 1 citedOpen Access
DDX3X acts as a selective dual switch regulator of mRNA translation in acute ER stress
2025Open Access
Plasticity of the mammalian integrated stress response
Nature·2025· 24 citedOpen Access
Author Reply to Peer Reviews of Mitochondrial dysfunction heightens the integrated stress response to drive ALS pathogenesis
2025
Lineage plasticity of the integrated stress response is a hallmark of cancer evolution
2025· 3 citedOpen Access
Phosphorylation of GCN2 by mTOR confers adaptation to conditions of hyper-mTOR activation under stress
Journal of Biological Chemistry·2024· 11 citedOpen Access
Mitochondrial dysfunction heightens the integrated stress response to drive ALS pathogenesis
2024· 5 citedOpen Access
Stem-loop-induced ribosome queuing in the uORF2/ATF4 overlap fine-tunes stress-induced human ATF4 translational control
Cell Reports·2024· 18 citedOpen Access
Mitochondrial ncRNA LDL-805 declines in alveolar epithelial type 2 cells of chronic obstructive pulmonary disease patients
2024· 1 citedOpen Access
Stress-induced β cell early senescence confers protection against type 1 diabetes
Cell Metabolism·2023· 40 citedOpen Access
Stem-loop induced ribosome queuing in the uORF2/ATF4 overlap fine-tunes stress-induced human ATF4 translational control
2023· 2 citedOpen Access
Biology of Stress Responses in Aging
2023· 8 citedOpen Access
Mitochondria-to-Nucleus Retrograde Signaling Via Mitochondrial DNA Encoded Non-coding RNA Regulates Mitochondrial Bioenergetics
2023
Supplementary Figure 1 from mTORC2 Balances AKT Activation and eIF2α Serine 51 Phosphorylation to Promote Survival under Stress
2023Open Access
Supplementary Figure 1 from mTORC2 Balances AKT Activation and eIF2α Serine 51 Phosphorylation to Promote Survival under Stress
2023Open Access
Data from mTORC2 Balances AKT Activation and eIF2α Serine 51 Phosphorylation to Promote Survival under Stress
2023· 1 citedOpen Access
Data from mTORC2 Balances AKT Activation and eIF2α Serine 51 Phosphorylation to Promote Survival under Stress
2023Open Access
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Frequent Co-authors

Martin D. Snider(14), Antonis E. Koromilas(12), Dawid Krokowski(11), Mithu Majumder(9), İbrahim Yaman(9), Anton A. Komar(8), James Fernandez(8), Randal J. Kaufman(7), Elena Bevilacqua(6), Chuanping Wang(6), William C. Merrick(5), Celvie L. Yuan(4), Mridusmita Saikia(4), Raul Jobava(4), Bo‐Jhih Guan(4), Ivan Topisirović(4), Wouter H. Lamers(4), Charlie Huang(4), Marc Parisien(3), Bo-Jhih Guan(3)