April Chen

Medicine · Health Sciences

16h-index932citations43works3.72yr avg
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Research Topics

Antibiotics Pharmacokinetics and Efficacy(12), Cancer Mechanisms and Therapy(11), Antibiotic Resistance in Bacteria(10), Liver physiology and pathology(6), Quinazolinone synthesis and applications(6)

Publications43 total

Identification, synthesis and characterization of a unique N-glucuronide of an acid metabolite of camizestrant (AZD9833) in humans
Drug Metabolism and Disposition·2026
Identification of novel, potent, and selective JAK2V617F inhibitors
Blood·2025Open Access
CRISPR-tica.ai: A function-informed generative modeling pipeline for prioritizing drug discovery in AML
Blood·2025Open Access
Hydrolysis of O-, N-, and N+-glucuronide metabolites in human feces
Drug Metabolism and Disposition·2025· 2 cited
Small molecule inhibitors of mannan-binding lectin-associated serine Proteases-2 and-3
European Journal of Medicinal Chemistry·2025· 1 cited
<i>Ex vivo</i> assessment of sulbactam-durlobactam clearance during continuous renal replacement therapy to guide dosing recommendations
Antimicrobial Agents and Chemotherapy·2024· 5 citedOpen Access
Fairness-Aware Graph Neural Networks: A Survey
ACM Transactions on Knowledge Discovery from Data·2024· 18 cited
<i>In vivo</i> dose response and efficacy of the β-lactamase inhibitor, durlobactam, in combination with sulbactam against the <i>Acinetobacter baumannii-calcoaceticus</i> complex
Antimicrobial Agents and Chemotherapy·2023· 9 citedOpen Access
<b> <i>I</i> </b> <i>n vitro</i> pharmacokinetics/pharmacodynamics of the β-lactamase inhibitor, durlobactam, in combination with sulbactam against <i>Acinetobacter baumannii-calcoaceticus</i> complex
Antimicrobial Agents and Chemotherapy·2023· 25 citedOpen Access
2526. <i>Ex Vivo</i> Assessment of Sulbactam-Durlobactam (SUL-DUR) Clearance during Continuous Renal Replacement Therapy (CRRT)
Open Forum Infectious Diseases·2023· 1 citedOpen Access
Enumerating numerical sets associated to a numerical semigroup
Discrete Applied Mathematics·2023Open Access
Fairness-Aware Graph Neural Networks: A Survey
arXiv (Cornell University)·2023Open Access
Supplementary Figure 1 from Identification of a Novel Recepteur d'Origine Nantais/c-Met Small-Molecule Kinase Inhibitor with Antitumor Activity &lt;i&gt;In vivo&lt;/i&gt;
2023Open Access
Data from Identification of a Novel Recepteur d'Origine Nantais/c-Met Small-Molecule Kinase Inhibitor with Antitumor Activity &lt;i&gt;In vivo&lt;/i&gt;
2023Open Access
Supplementary Figure 2 from Identification of a Novel Recepteur d'Origine Nantais/c-Met Small-Molecule Kinase Inhibitor with Antitumor Activity &lt;i&gt;In vivo&lt;/i&gt;
2023Open Access
Supplementary Figure 2 from Identification of a Novel Recepteur d'Origine Nantais/c-Met Small-Molecule Kinase Inhibitor with Antitumor Activity &lt;i&gt;In vivo&lt;/i&gt;
2023Open Access
Supplementary Figure Legends 1-3 from Identification of a Novel Recepteur d'Origine Nantais/c-Met Small-Molecule Kinase Inhibitor with Antitumor Activity &lt;i&gt;In vivo&lt;/i&gt;
2023Open Access
Supplementary Figure Legends 1-3 from Identification of a Novel Recepteur d'Origine Nantais/c-Met Small-Molecule Kinase Inhibitor with Antitumor Activity &lt;i&gt;In vivo&lt;/i&gt;
2023Open Access
Supplementary Figure 3 from Identification of a Novel Recepteur d'Origine Nantais/c-Met Small-Molecule Kinase Inhibitor with Antitumor Activity &lt;i&gt;In vivo&lt;/i&gt;
2023Open Access
Supplementary Figure 1 from Identification of a Novel Recepteur d'Origine Nantais/c-Met Small-Molecule Kinase Inhibitor with Antitumor Activity &lt;i&gt;In vivo&lt;/i&gt;
2023Open Access
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Frequent Co-authors

Isabelle Dussault(16), Paula Kaplan‐Lefko(16), Karen Rex(16), Jasmine Lin(14), Jodi Moriguchi(14), Monica Reese(12), Yihong Zhang(12), Yajing Yang(12), Angela Coxon(12), Teresa L. Burgess(12), Tao Osgood(11), Bethany Mattson(11), Tae‐Seong Kim(8), Loren Berry(7), Alita A. Miller(7), Adam B. Shapiro(7), John P. O’Donnell(6), Rubén Tommasi(6), Jean-Christophe Harmange(5), Roman Shimanovich(5)