Geming Lu

Medicine · Health Sciences

18h-index1.7kcitations79works3.82yr avg
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Research Topics

Pancreatic function and diabetes(31), Immune Cell Function and Interaction(20), Diabetes and associated disorders(20), T-cell and B-cell Immunology(11), Immune cells in cancer(11)

Publications79 total

Selective disruption of RORγt-CBFβ interaction by IMU-935 prevents RORγt-dependent Th17 autoimmunity but not thymocyte development
Journal of Clinical Investigation·2026Open Access
Human pancreatic α-cell heterogeneity and trajectory inference analyses reveal SMOC1 as a β-cell dedifferentiation gene
Nature Communications·2025· 2 citedOpen Access
A simple approach of nuclei isolation for single nucleus multiome sequencing
Journal of Molecular and Cellular Cardiology·2025
321-OR: ADA Presidents' Select Abstract: FOXO1 Is Vital for Gestational Beta-Cell Compensation to Protect Against Gestational Diabetes
Diabetes·2025
1846-P: Human α-Cell Heterogeneity and Trajectory Inference Analyses of Human Islets Reveal SMOC1 as a β-Cell Dedifferentiation Gene
Diabetes·2025
77-OR: BNIP3-Mediated Mitophagy Protects Human β-Cells by Regulating Mitochondrial Integrity and Immunogenicity in Type 1 Diabetes (T1D)
Diabetes·2025· 1 cited
1831-P: Selective Induction of Spliced XBP1 in Pancreatic Islet Beta Cells Causes Reversible Diabetes
Diabetes·2025
Shared-aperture Broadband Phased Array Antenna for LEO Satellite Communication
2025
LGR4 is essential for maintaining β-cell homeostasis through suppression of RANK
Molecular Metabolism·2025· 2 citedOpen Access
Cycling alpha cells in regenerative drug-treated human pancreatic islets may serve as key beta cell progenitors
Cell Reports Medicine·2024· 12 citedOpen Access
A Phase 1 single ascending dose study of pure oral harmine in healthy volunteers
Journal of Psychopharmacology·2024· 13 citedOpen Access
Harmine and exendin-4 combination therapy safely expands human β cell mass in vivo in a mouse xenograft system
Science Translational Medicine·2024· 23 citedOpen Access
339-OR: Enhanced Expression of Zinc Finger Protein 385D Leads to Type 2 Diabetes Phenotype in Human Beta Cells
Diabetes·2024
1720-P: Single Nucleus Transcriptome Profiling of Human Islet Cells under Metabolic Stress In Vivo
Diabetes·2024
Cholesterol 25‐Hydroxylase Protects Against Diabetic Kidney Disease by Regulating ADP Ribosylation Factor 4
Advanced Science·2024· 7 citedOpen Access
LGR4 is essential for maintaining β-cell homeostasis through suppression of RANK
2024· 1 citedOpen Access
Human Pancreatic α-Cell Heterogeneity and Trajectory Inference Analysis Using Integrated Single Cell- and Single Nucleus-RNA Sequencing Platforms
2023· 2 citedOpen Access
Single Cell RNA-Seq Analysis of Regenerative Drug-Treated Human Pancreatic Islets Identifies A Cycling Alpha Cell Population As Key Beta Cell Progenitors
2023· 2 citedOpen Access
350-OR: Transcriptomics Identification of a-Cell Subpopulations in Human Islets Using Integrated scRNA-seq and snRNA-seq
Diabetes·2023
235-OR: Myc Activity Is Required for Mitochondrial Function and Glucose-Stimulated Insulin Secretion (GSIS) in Pancreatic ß-Cells
Diabetes·2023
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Frequent Co-authors

Adolfo Garcı́a-Ocaña(19), Huabao Xiong(14), Zihan Zheng(10), Randy B. Kang(10), Andrew F. Stewart(10), Donald K. Scott(10), Carolina Rosselot(9), Jianjun Yang(8), Tuo Zhang(8), Liang Peng(7), Andrew G. Sikora(7), Padmini Jayaraman(6), John Cijiang He(6), Huabao Xiong(6), Miao Cui(6), Yansui Li(6), Martin J. Walsh(5), Ming‐Ming Zhou(5), Yuan Hu(5), Feihong Xu(5)