Malachi Griffith

James S. McDonnell Foundation — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

70h-index25.3kcitations640works2.72yr avg
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Research Topics

Cancer Genomics and Diagnostics(213), Lymphoma Diagnosis and Treatment(91), Genomics and Rare Diseases(75), Genetic factors in colorectal cancer(71), Immunotherapy and Immune Responses(58)

Publications639 total

CIViC MCP: Integrating Large Language Models with the Clinical Interpretations of Variants in Cancer
2025· 1 citedOpen Access
Abstract A021: Standardized Oncogenic Classification Guidance of Critical Diagnostic and Therapeutic markers in pediatric cancers: NTRK fusions
Cancer Research·2025
Evaluating Language Models for Biomedical Fact-Checking: A Benchmark Dataset for Cancer Variant Interpretation Verification
2025· 2 citedOpen Access
Multi-Platform Curation in the Development of ACMG/AMP Specifications for Von Hippel Lindau (VHL) Disease
2025Open Access
CeRTS: certainty retrieval token search in large language model clinical information extraction
Journal of Biomedical Informatics·2025Open Access
Informatics at the Frontier of Cancer Research
Cancer Research·2025Open Access
Role of the CTCF binding site in Human T-Cell Leukemia Virus-1 pathogenesis
PLoS Pathogens·2025Open Access
5 | LARGE B‐CELL LYMPHOMA MICROENVIRONMENT ARCHETYPE PROFILES (LYMPHOMAPS) IDENTIFY SUBGROUPS WITH GREATEST BENEFIT FROM CD19 CAR T‐CELL THERAPY
Hematological Oncology·2025· 1 citedOpen Access
Cataloging genomic and transcriptomic features of relapsed SCLC.
Journal of Clinical Oncology·2025
Looking Forward to AI and Medicine: Where Are We, and Where Are We Going?
PubMed·2025· 1 citedOpen Access
Deep Sequencing Reveals Somatic Mosaicism in Genes Relevant to Genetic Errors of Immunity in a Cohort of Patients with Immune Dysregulation
Journal of Human Immunity·2025Open Access
Abstract 1075: Piloting NTRK fusion-specific oncogenicity guidelines - lessons learned
Cancer Research·2025
Abstract 3371: Gene deletions in estrogen receptor positive HER2-negative breast cancer are associated with worse outcome than predicted by diagnostic-grade gene expression assays
Cancer Research·2025
Identifying genetic errors of immunity due to mosaicism
The Journal of Experimental Medicine·2025· 5 cited
Single-Cell Transcriptomic Analysis of Kaposi Sarcoma
PLoS Pathogens·2025· 4 citedOpen Access
Abstract B121: Personalized neoantigen vaccine-based therapies in syngeneic mouse models of lymphoma: Development of neoantigen-specific immunotherapies for mouse A20 lymphoma
Cancer Immunology Research·2025
Clinico-genomic features predict distinct metastatic phenotypes in cutaneous melanoma
2025Open Access
The Hao-Fountain syndrome protein USP7 regulates neuronal connectivity in the brain via a novel p53-independent ubiquitin signaling pathway
Cell Reports·2025· 9 citedOpen Access
Certs: Certainty Retrieval Token Search in Large Language Model Clinical Information Extraction
SSRN Electronic Journal·2025Open Access
Neoantigen DNA vaccines are safe, feasible, and induce neoantigen-specific immune responses in triple-negative breast cancer patients
Genome Medicine·2024· 56 citedOpen Access
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Frequent Co-authors

Obi L. Griffith(34), Elaine R. Mardis(16), Steven J.M. Jones(11), Marco A. Marra(11), Richard K. Wilson(11), Martin Hirst(10), Alex H. Wagner(10), Robert S. Fulton(9), Nicholas C. Spies(9), Kilannin Krysiak(9), Thomas Zeng(8), Jason Walker(8), Zachary L. Skidmore(8), Christopher A. Miller(8), Yongjun Zhao(7), Adam Coffman(7), Joshua F. McMichael(7), Jasreet Hundal(7), Benjamin J. Ainscough(6), Katie M. Campbell(6)