Ricardo Miledi

University of California, Irvine — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

93h-index35.4kcitations493works0.02yr avg
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Research Topics

Ion channel regulation and function(208), Neuroscience and Neuropharmacology Research(153), Neuroscience and Neural Engineering(137), Nicotinic Acetylcholine Receptors Study(74), Photoreceptor and optogenetics research(62)

Publications491 total

Tonic Calcium-Activated Chloride Current Sustained by ATP Release and Highly Desensitizing Human P2X1 Receptors
Neuroscience·2019· 1 citedOpen Access
Behavioral changes induced through adenosine A2A receptor ligands in a rat depression model induced by olfactory bulbectomy
Brain and Behavior·2018· 40 citedOpen Access
Repression of nicotinic acetylcholine receptor expression by antisense RNAs and an oligonucleotide (Xenopus oocytes/Torpedo/hybrid-arrested translation/membrane currents/chloride channels)
2017
Theobromine-Induced Changes in A1 Purinergic Receptor Gene Expression and Distribution in a Rat Brain Alzheimer’s Disease Model
Journal of Alzheimer s Disease·2016· 32 cited
GABAρ selective antagonist TPMPA partially inhibits GABA-mediated currents recorded from neurones and astrocytes in mouse striatum
Neuropharmacology·2016· 8 cited
Differential gene expression patterns and colocalization of ATP-gated P2X6/P2X4 ion channels during rat small intestine ontogeny
Gene Expression Patterns·2016· 3 cited
Acetylcholine receptors from human muscle as pharmacological targets for ALS therapy
Proceedings of the National Academy of Sciences·2016· 68 citedOpen Access
Dipicrylamine Modulates GABAρ1 Receptors through Interactions with Residues in the TM4 and Cys-Loop Domains
Molecular Pharmacology·2016· 7 cited
Change in desensitization of cat muscle acetylcholine receptor caused by coexpression of Torpedo acetylcholine receptor subunits in Xenopus oocytes (nicotinic acetylcholine receptors/hybrid receptors/cat denervated muscles)
2016
Expressional potency of mRNAs encoding receptors and voltage-activated channels in the postmortem rat brain (Xenopus oocytes/mRNA stability/neurotransmitter receptors/Northern blot/electrophysiology)
2016
Anorexia Reduces GFAP+ Cell Density in the Rat Hippocampus
Neural Plasticity·2016· 31 citedOpen Access
Direct evidence for GABAergic activity of Withania somnifera on mammalian ionotropic GABAA and GABAρ receptors
Journal of Ethnopharmacology·2015· 71 cited
Expression of hippocampal serotonin receptors 5‐HT<sub>2C</sub> and 5‐HT<sub>5A</sub> in a rat model of diet‐induced obesity supplemented with tryptophan
International Journal of Developmental Neuroscience·2015· 13 cited
Dehydration-Induced Anorexia Reduces Astrocyte Density in the Rat Corpus Callosum
Neural Plasticity·2015· 29 citedOpen Access
GABAρ subunits confer a bicuculline-insensitive component to GFAP<sup>+</sup>cells of cerebellum
Proceedings of the National Academy of Sciences·2014· 20 citedOpen Access
Modulation of GABA-A receptors of astrocytes and STC-1 cells by taurine structural analogs
Amino Acids·2014· 5 cited
Nicotinic and muscarinic agonists and acetylcholinesterase inhibitors stimulate a common pathway to enhance GluN2B-NMDAR responses
Proceedings of the National Academy of Sciences·2014· 22 citedOpen Access
TMEM16A alternative splicing isoforms in Xenopus tropicalis: Distribution and functional properties
Biochemical and Biophysical Research Communications·2014· 6 cited
Analysis of free ACh and 5-HT in milk from four different species and their bioactivity on 5-HT<sub>3</sub>and nACh receptors
Food & Function·2014· 7 cited
Anion permeation in calcium-activated chloride channels formed by TMEM16A from Xenopus tropicalis
Pflügers Archiv - European Journal of Physiology·2013· 20 cited
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Frequent Co-authors

B. Katz(12), Bernard Katz(7), Clarke R. Slater(3), Kazuo Kusano(2), J. Stinnakre(2), Lincoln T. Potter(2), Ian Parker(2), Gábor Tigyi(2), K. Krnjević(2), R. I. Birks(1), Jared M. Diamond(1), P B Molinoff(1), Carlos Matute(1), Marı́a Victoria Sánchez-Gómez(1), Luis Martínez‐Millán(1), Eleonora Palma(1), Mascia Amici(1), Fabrizia Sobrero(1), Gabriele Spinelli(1), Silvia Di Angelantonio(1)