Jake Saklatvala

King's College London — United Kingdom

Immunology and Microbiology · Life Sciences

11h-index535citations43works5.82yr avg
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Research Topics

Psoriasis: Treatment and Pathogenesis(13), Asthma and respiratory diseases(10), Dermatology and Skin Diseases(9), Acne and Rosacea Treatments and Effects(9), Retinoids in leukemia and cellular processes(8)

Publications43 total

Genetic liability to psoriasis predicts severe disease outcomes
Genome Medicine·2025Open Access
The Skin Genetics Consortium
British Journal of Dermatology·2025Open Access
Genetic proxies of GLP1R expression in whole blood are associated with lower risk of psoriasis and psoriatic arthritis
2025Open Access
Multi-omic triangulation identifies molecular candidates of atopic dermatitis severity
2025Open Access
The polygenic architecture of hidradenitis suppurativa reveals signaling mechanisms that implicate epithelial remodeling
2025· 1 citedOpen Access
0564 Hidradenitis suppurativa GWAS identifies 12 loci that implicate misdirected keratinocyte migration in pathogenesis
Journal of Investigative Dermatology·2025
Genome-wide association meta-regression identifies stem cell lineage orchestration as a key driver of acne risk
2025Open Access
O10 Acne polygenic risk score derived from genome-wide association metaregression enables prediction of severity
British Journal of Dermatology·2025· 1 citedOpen Access
Investigating the Genetic Basis of the Influence of Adiposity on Psoriasis: A Cross-Sectional Study in a Large United Kingdom Population–Based Biobank
Journal of Investigative Dermatology·2025· 4 citedOpen Access
Genetic liability to psoriasis predicts severe disease outcomes
2025Open Access
GWAS meta-analysis of psoriasis identifies new susceptibility alleles impacting disease mechanisms and therapeutic targets
Nature Communications·2025· 38 citedOpen Access
GWAS Meta-Analysis Identifies Susceptibility Loci for Keloids and Hypertrophic Scarring in Europeans
Journal of Investigative Dermatology·2024· 3 citedOpen Access
Exploring the Link Between Genetic Predictors of Cardiovascular Disease and Psoriasis
JAMA Cardiology·2024· 18 citedOpen Access
418 Hidradenitis suppurativa risk alleles identified in an ancestrally diverse HS meta-analysis of 16 cohorts
Journal of Investigative Dermatology·2024Open Access
A genome-wide meta-analysis of palmoplantar pustulosis implicates TH2 responses and cigarette smoking in disease pathogenesis
Journal of Allergy and Clinical Immunology·2024· 16 citedOpen Access
O11 Investigating the genetic basis of the influence of adiposity on psoriasis
British Journal of Dermatology·2024
Defining disease severity in atopic dermatitis and psoriasis for the application to biomarker research: an interdisciplinary perspective
British Journal of Dermatology·2024· 21 citedOpen Access
A genome-wide meta-analysis of palmoplantar pustulosis implicates Th2 responses and cigarette smoking in disease pathogenesis
2024· 3 citedOpen Access
GWAS meta-analysis of psoriasis identifies new susceptibility alleles impacting disease mechanisms and therapeutic targets
2023· 29 citedOpen Access
Genome-wide meta-analysis implicates variation affecting mast cell biology in urticaria
Journal of Allergy and Clinical Immunology·2023· 7 citedOpen Access
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Frequent Co-authors

Nick Dand(35), Catherine Smith(28), Juliet N. Barker(26), Michael A. Simpson(25), Ravi Ramessur(14), Laurent F. Thomas(14), Mari Løset(14), Satveer K. Mahil(11), Külli Kingo(10), Paola Di Meglio(9), Kristian Hveem(9), C.E.M. Griffiths(8), Charles Curtis(7), Emanuele de Rinaldis(7), Maris Teder‐Laving(7), Lam C. Tsoi(7), Lavinia Paternoster(7), David Baudry(6), Stephan Weidinger(6), Josine L. Min(6)