Nicholas S. Tolwinski

Duke-NUS Medical School — Singapore

Biochemistry, Genetics and Molecular Biology · Life Sciences

32h-index3.4kcitations89works9.82yr avg
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Research Topics

Wnt/β-catenin signaling in development and cancer(27), Genetics, Aging, and Longevity in Model Organisms(19), Developmental Biology and Gene Regulation(17), Cancer-related gene regulation(16), Hippo pathway signaling and YAP/TAZ(10)

Publications89 total

Review of: "Aging as Cybernetic Attractor Decay: Beyond the Stochastic-Programmed Dichotomy"
2026Open Access
Partial Reprogramming Is Conserved from Insect to Mammal
Cells·2026Open Access
Principal component-based clinical aging clocks identify signatures of healthy aging and targets for clinical intervention
Nature Aging·2024· 51 citedOpen Access
Evaluating the inter-species transmission risk of amyloid beta peptide aggregates via ingestion
Alzheimer s Research & Therapy·2024· 2 citedOpen Access
Drosophila—A Model System for Developmental Biology
Journal of Developmental Biology·2024· 4 citedOpen Access
The Wnt Co-Receptor PTK7/Otk and Its Homolog Otk-2 in Neurogenesis and Patterning
Cells·2024· 2 citedOpen Access
ggbulksurv: An R package for easy Drosophila and C. elegans survival analysis
PubMed·2023· 1 citedOpen Access
The principal component-based clinical aging clock (PCAge) identifies signatures of healthy aging and provides normative targets for clinical intervention
Research Square (Research Square)·2023Open Access
Evaluating the transmission risk of amyloid beta peptide via ingestion
2023Open Access
The principal component-based clinical aging clock (PCAge) identifies signatures of healthy aging and provides normative targets for clinical intervention
2023· 4 citedOpen Access
Using Optogenetics to Model Cellular Effects of Alzheimer’s Disease
International Journal of Molecular Sciences·2023· 7 citedOpen Access
Optogenetics as a Tool to Study Neurodegeneration and Signal Transduction
2022
Combining stem cell rejuvenation and senescence targeting to synergistically extend lifespan
Aging·2022· 16 citedOpen Access
MCC is a centrosomal protein that relocalizes to non-centrosomal apical sites during intestinal cell differentiation
Journal of Cell Science·2022· 2 citedOpen Access
LipidClock: A Lipid-Based Predictor of Biological Age
Frontiers in Aging·2022· 17 citedOpen Access
A non-canonical Raf function is required for dorsal–ventral patterning during Drosophila embryogenesis
Scientific Reports·2022· 2 citedOpen Access
Combining Stem Cell Rejuvenation and Senescence Targeting to Synergistically Extend Lifespan
2022· 3 citedOpen Access
Wnt Signaling Rescues Amyloid Beta-Induced Gut Stem Cell Loss
Cells·2022· 11 citedOpen Access
Wnt signaling rescues amyloid beta induced stem cell loss
2021Open Access
A Non-Canonical Raf Function Is Required for Dorsal-Ventral Patterning During <i>Drosophila</i> Embryogenesis
2021Open Access
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Frequent Co-authors

Jan Gruber(13), Prameet Kaur(11), Emelyne Teo(6), Eric Wieschaus(5), Nicole Kaplan(5), Amaury Cazenave‐Gassiot(5), Markus R. Wenk(5), Sheng Fong(5), Natalie G. Ahn(4), Jahnavi Suresh(4), Diogo Barardo(4), Li Fang Ng(4), Vanessa Yuk Man Lam(4), Paul Shapiro(3), Krishna Chaithanya Batchu(3), Barry Halliwell(3), Pamela F. Colosimo(3), Jay B. Lusk(3), Anupriya Ramamoorthy(3), Anne M. Whalen(2)