Jagan M.R. Pongubala

University of Hyderabad — India

Immunology and Microbiology · Life Sciences

20h-index2.2kcitations28works0.02yr avg
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Research Topics

T-cell and B-cell Immunology(11), NF-κB Signaling Pathways(7), Immune Cell Function and Interaction(6), Reproductive System and Pregnancy(5), Estrogen and related hormone effects(4)

Publications28 total

Discovery of dynamic changes in 3D chromatin architecture through polymer physics model
2024Open Access
A regulatory network of microRNAs confers lineage commitment during early developmental trajectories of B and T lymphocytes
Proceedings of the National Academy of Sciences·2021· 10 citedOpen Access
The RAG1 N-terminal region regulates the efficiency and pathways of synapsis for V(D)J recombination
The Journal of Experimental Medicine·2021· 23 citedOpen Access
Spatial Organization of Chromatin: Transcriptional Control of Adaptive Immune Cell Development
Frontiers in Immunology·2021· 27 citedOpen Access
Developmentally regulated higher-order chromatin interactions orchestrate B cell fate commitment
Nucleic Acids Research·2017· 33 citedOpen Access
Gene regulatory networks directing myeloid and lymphoid cell fates within the immune system
Seminars in Immunology·2008· 106 cited
EBF restricts alternate lineage options and promotes B cell fate commitment independently of Pax5
The FASEB Journal·2008
Regulation of Immunoglobulin Light-Chain Recombination by the Transcription Factor IRF-4 and the Attenuation of Interleukin-7 Signaling
Immunity·2008· 185 citedOpen Access
Transcription factor EBF restricts alternative lineage options and promotes B cell fate commitment independently of Pax5
Nature Immunology·2008· 252 cited
Gene Regulatory Networks that Orchestrate the Development of B Lymphocyte Precursors
Advances in experimental medicine and biology·2007· 32 cited
Gene regulatory networks and the determination of lymphoid cell fates
Current Opinion in Immunology·2006· 22 cited
Contingent gene regulatory networks and B cell fate specification
Proceedings of the National Academy of Sciences·2005· 189 citedOpen Access
Assembling a Gene Regulatory Network for Specification of the B Cell Fate
Developmental Cell·2004· 234 citedOpen Access
Crystal Structure of PU.1/IRF-4/DNA Ternary Complex
Molecular Cell·2002· 155 citedOpen Access
Modification of multiple transcriptional regulatory elements in a Moloney murine leukemia virus gene transfer vector circumvents silencing in fibroblast grafts and increases levels of expression of the transferred enzyme
Gene Therapy·2002· 9 cited
Normal Myeloid Development Requires Both the Glutamine-Rich Transactivation Domain and the PEST Region of Transcription Factor PU.1 but Not the Potent Acidic Transactivation Domain
Molecular and Cellular Biology·1998· 47 citedOpen Access
PU.1 can participate in an active enhancer complex without its transcriptional activation domain
Proceedings of the National Academy of Sciences·1997· 86 citedOpen Access
Multiple proteins physically interact with PU.1. Transcriptional synergy with NF-IL6 β (C/EBP δ, CRP3)
The Journal of Immunology·1995· 111 cited
Activating Transcription Factor 1 and Cyclic AMP Response Element Modulator Can Modulate the Activity of the Immunoglobulin κ 3′ Enhancer
Journal of Biological Chemistry·1995· 38 citedOpen Access
PU.1 Recruits a Second Nuclear Factor to a Site Important for Immunoglobulin κ 3' Enhancer Activity
Molecular and Cellular Biology·1992· 107 cited
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Frequent Co-authors

Harinder Singh(8), Michael L. Atchison(6), Kay L. Medina(5), C.P. Puri(5), D W Lancki(4), W. Elger(4), Sujatha Nagulapalli(3), Rudolf Grosschedl(3), Anurupa Devi Yadavalli(3), Scott R. McKercher(2), Daniel Northrup(2), Thomas Treiber(2), Eric Bertolino(2), Matthew Thomas(2), David Allman(2), Michael L. Atchison(2), Sameena Nikhat(2), Dasaradhi Palakodeti(2), Cornelis Murre(2), Rohini Patil(2)