Rajkumar Lalji Sahani

Virginia Commonwealth University — United States

Materials Science · Physical Sciences

16h-index1.2kcitations55works1.82yr avg
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Research Topics

Crystallization and Solubility Studies(26), X-ray Diffraction in Crystallography(26), Catalytic Alkyne Reactions(15), Catalytic C–H Functionalization Methods(10), HIV/AIDS drug development and treatment(9)

Publications55 total

Development of a Scalable Synthetic Route to (1 <i>R</i> ,5 <i>R</i> )-2,2-Dimethoxybicyclo[3.1.0]hexan-3-one: An Important Intermediate in the Synthesis of Lenacapavir
Organic Process Research & Development·2025Open Access
Development of a scalable synthetic route to (1R,5R)-2,2-dimethoxybicyclo[3.1.0]hexan-3-one: an important intermediate in the synthesis of lenacapavir
2025
Development of a scalable synthetic route to (1R,5R)-2,2-dimethoxybicyclo[3.1.0]hexan-3-one: an important intermediate in the synthesis of lenacapavir
2024· 1 citedOpen Access
Synthetic Process Development of ( <i>R</i> )-(+)-1,2-Epoxy-5-hexene: An Important Chiral Building Block
Organic Process Research & Development·2024· 2 citedOpen Access
Synthetic process development of (R)-(+)-1,2-epoxy-5-hexene: an important chiral building block
2024· 1 citedOpen Access
Synthesis of Chiral 1,2-Amino Alcohol-Containing Compounds Utilizing Ruthenium-Catalyzed Asymmetric Transfer Hydrogenation of Unprotected α-Ketoamines
The Journal of Organic Chemistry·2024· 7 cited
Discovery of N-benzyl hydroxypyridone carboxamides as a novel and potent antiviral chemotype against human cytomegalovirus (HCMV)
Acta Pharmaceutica Sinica B·2021· 9 citedOpen Access
Metal binding 6-arylthio-3-hydroxypyrimidine-2,4-diones inhibited human cytomegalovirus by targeting the pUL89 endonuclease of the terminase complex
European Journal of Medicinal Chemistry·2021· 7 citedOpen Access
Design, Synthesis and Characterization of HIV-1 CA-Targeting Small Molecules: Conformational Restriction of PF74
Viruses·2021· 16 citedOpen Access
Potency and metabolic stability: a molecular hybrid case in the design of novel PF74-like small molecules targeting HIV-1 capsid protein
RSC Medicinal Chemistry·2021· 4 citedOpen Access
Nitrene Transfer and Carbene Transfer in Gold Catalysis
Chemical Reviews·2020· 370 cited
Novel PF74-like small molecules targeting the HIV-1 capsid protein: Balance of potency and metabolic stability
Acta Pharmaceutica Sinica B·2020· 32 citedOpen Access
Novel HIV-1 capsid-targeting small molecules of the PF74 binding site
European Journal of Medicinal Chemistry·2020· 27 citedOpen Access
Chemical profiling of HIV-1 capsid-targeting antiviral PF74
European Journal of Medicinal Chemistry·2020· 25 citedOpen Access
Toward Structurally Novel and Metabolically Stable HIV-1 Capsid-Targeting Small Molecules
Viruses·2020· 29 citedOpen Access
Synthesis of nitrogen-containing molecules via transition metal-catalyzed reactions on isoxazoles, anthranils and benzoisoxazoles
Advances in organometallic chemistry·2020· 41 cited
CCDC 1904910: Experimental Crystal Structure Determination
The Cambridge Structural Database·2019Open Access
CCDC 1904912: Experimental Crystal Structure Determination
The Cambridge Structural Database·2019Open Access
CCDC 1904909: Experimental Crystal Structure Determination
The Cambridge Structural Database·2019Open Access
CCDC 1904908: Experimental Crystal Structure Determination
The Cambridge Structural Database·2019Open Access
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Frequent Co-authors

Rai‐Shung Liu(21), Rai‐Shung Liu(14), Jiashu Xie(8), Zhengqiang Wang(8), Lei Wang(6), Karen A. Kirby(6), Huanchun Zhang(6), Stefan G. Sarafianos(6), B. Frank Gupton(6), Samir Kundlik Pawar(5), Sachin Bhausaheb Wagh(5), Mary C. Casey(5), Sanjeev Kumar V. Vernekar(5), Haijuan Du(5), Philip R. Tedbury(5), Daryl Guthrie(5), John M. Saathoff(5), Aline Souza(5), Justina M. Burns(5), Douglas A. Klumpp(5)