Michael A. Calderwood

Harvard University — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

32h-index7.8kcitations88works14.02yr avg
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Research Topics

Bioinformatics and Genomic Networks(32), Viral-associated cancers and disorders(17), Cytomegalovirus and herpesvirus research(16), RNA and protein synthesis mechanisms(11), Herpesvirus Infections and Treatments(11)

Publications88 total

Dynamic engagement of dual-role regulators by the Sin3 complex
2026Open Access
A scalable approach to resolving variants of uncertain significance
2026Open Access
Effector–host interactome map links type III secretion systems in healthy gut microbiomes to immune modulation
Nature Microbiology·2026Open Access
Predicting interaction-specific protein–protein interaction perturbations by missense variants with MutPred-PPI
2025Open Access
The IGVF catalog—from genetic variation to function
Nucleic Acids Research·2025· 3 citedOpen Access
Widespread variation in molecular interactions and regulatory properties among transcription factor isoforms
Molecular Cell·2025· 21 citedOpen Access
A comprehensive two-hybrid analysis to explore the <i>Legionella pneumophila</i> effector–effector interactome
mSystems·2024· 5 citedOpen Access
Pervasive mislocalization of pathogenic coding variants underlying human disorders
Cell·2024· 39 citedOpen Access
Deciphering the impact of genomic variation on function
Nature·2024· 67 citedOpen Access
A comprehensive two-hybrid analysis to explore the <i>L. pneumophila</i> effector-effector interactome
2024· 2 citedOpen Access
Widespread variation in molecular interactions and regulatory properties among transcription factor isoforms
2024· 11 citedOpen Access
AI-guided pipeline for protein–protein interaction drug discovery identifies a SARS-CoV-2 inhibitor
Molecular Systems Biology·2024· 20 citedOpen Access
AI-guided pipeline for protein-protein interaction drug discovery identifies a SARS-CoV-2 inhibitor
2023· 5 citedOpen Access
N-terminal proteoforms may engage in different protein complexes
Life Science Alliance·2023· 5 citedOpen Access
Next-generation large-scale binary protein interaction network for Drosophila melanogaster
Nature Communications·2023· 38 citedOpen Access
Assessment of community efforts to advance network-based prediction of protein–protein interactions
Nature Communications·2023· 41 citedOpen Access
Author Correction: Protein interaction network of alternatively spliced isoforms from brain links genetic risk factors for autism
Nature Communications·2023· 1 citedOpen Access
N-terminal proteoforms may engage in different protein complexes
2023· 1 citedOpen Access
Expanding the HDAC druggable landscape beyond enzymatic activity
2022· 1 citedOpen Access
EROS is a selective chaperone regulating the phagocyte NADPH oxidase and purinergic signalling
eLife·2022· 15 citedOpen Access
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Frequent Co-authors

Marc Vidal(29), David E. Hill(24), Tong Hao(21), Frederick P. Roth(15), Kerstin Spirohn(14), Jean‐Claude Twizere(12), Eric Johannsen(10), Benoît Charloteaux(9), Katja Luck(9), Yun Shen(9), Adrian Whitehouse(9), Nidhi Sahni(8), Dawit Balcha(8), Albert-Ĺaszló Barabási(8), Dae‐Kyum Kim(8), L. Lambourne(8), I. Kovács(8), Yves Jacob(8), Thomas Rolland(7), Quan Zhong(7)