Bryan W. Sherman

Gramercy Research Group (United States) — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

8h-index469citations13works0.02yr avg
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Research Topics

Receptor Mechanisms and Signaling(5), Glaucoma and retinal disorders(4), Flavonoids in Medical Research(4), Protein Kinase Regulation and GTPase Signaling(2), Neuropeptides and Animal Physiology(2)

Publications13 total

グローバル人材の育成―大学での留学制度の活用からグローバル・コンピテンシーへの発展―
応用心理学研究·2020
Discovery and Preclinical Development of Netarsudil, a Novel Ocular Hypotensive Agent for the Treatment of Glaucoma
Journal of Ocular Pharmacology and Therapeutics·2017· 181 citedOpen Access
Discovery of the ROCK inhibitor netarsudil for the treatment of open-angle glaucoma
Bioorganic & Medicinal Chemistry Letters·2016· 104 citedOpen Access
IOP-lowering Efficacy And Tolerability Of AR-13324, A Dual Mechanism Kinase Inhibitor For The Treatment Of Glaucoma
2012· 3 cited
Discovery and SAR of a Class of Ocularly-active Compounds Displaying a Dual Mechanism of Activity for the Treatment of Glaucoma
2012· 5 cited
Discovery and in vitro SAR of AR-12286, a Potent Kinase Inhibitor for the Treatment of Glaucoma
2009· 8 cited
Synthesis and evaluation of potent and selective β3 adrenergic receptor agonists containing heterobiaryl carboxylic acids
Bioorganic & Medicinal Chemistry Letters·2007· 19 citedOpen Access
Biarylaniline Phenethanolamines as Potent and Selective β<sub>3</sub>Adrenergic Receptor Agonists
Journal of Medicinal Chemistry·2006· 41 citedOpen Access
2‐(Anilinomethyl)imidazolines as α<sub>1</sub> Adrenergic Receptor Agonists: α<sub>1a</sub> Subtype Selective 2′‐Heteroaryl Compounds.
ChemInform·2003
2-(Anilinomethyl)imidazolines as α1 adrenergic receptor agonists: α1a subtype selective 2′-heteroaryl compounds
Bioorganic & Medicinal Chemistry Letters·2003· 16 citedOpen Access
α1-Adrenoceptor activation: A comparison of 4-(Anilinomethyl)imidazoles and 4-(Phenoxymethyl)imidazoles to related 2-imidazolines
Bioorganic & Medicinal Chemistry Letters·2002· 5 citedOpen Access
2-(Anilinomethyl)imidazolines as α<sub>1</sub> Adrenergic Receptor Agonists:  the Discovery of α<sub>1</sub><sub>a</sub> Subtype Selective 2‘-Alkylsulfonyl-Substituted Analogues
Journal of Medicinal Chemistry·2002· 25 citedOpen Access
Synthesis and Evaluation of Potent and Selective β<sub>3</sub> Adrenergic Receptor Agonists Containing Acylsulfonamide, Sulfonylsulfonamide, and Sulfonylurea Carboxylic Acid Isosteres
Journal of Medicinal Chemistry·2001· 62 citedOpen Access

Frequent Co-authors

Mitchell A. deLong(5), Casey Kopczynski(5), Cheng‐Wen Lin(4), Carmen Laethem(4), Jill M. Sturdivant(4), Stephen J. Hodson(4), Michael J. Bishop(4), Jason D. Speake(4), Frank Navas(4), Deanna T. Garrison(4), Eric C. Bigham(4), David L. Saussy(4), Paul E Irving(4), Jeffrey D. Yingling(3), David Uehling(3), David N. Deaton(3), Conrad L. Cowan(3), Geoff Heintzelman(3), Lori Moore(2), Susan M. Royalty(2)