John Mansfield

Cystic Fibrosis Trust — United Kingdom

Biochemistry, Genetics and Molecular Biology · Life Sciences

52h-index36.5kcitations158works40.02yr avg
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Research Topics

Inflammatory Bowel Disease(100), Microscopic Colitis(45), Helicobacter pylori-related gastroenterology studies(31), Immunodeficiency and Autoimmune Disorders(22), Eosinophilic Esophagitis(18)

Publications144 total

P151 Added benefit of triple therapy for cystic fibrosis patients with Phe508del–gating genotype: a real-world prospective study
Journal of Cystic Fibrosis·2024
Defining predictors of responsiveness to advanced therapies in Crohn’s disease and ulcerative colitis: protocol for the IBD-RESPONSE and nested CD-metaRESPONSE prospective, multicentre, observational cohort study in precision medicine
BMJ Open·2024· 11 citedOpen Access
Conserved γδ T cell selection by BTNL proteins limits progression of human inflammatory bowel disease
Science·2023· 60 citedOpen Access
Dose escalation randomised study of efmarodocokin alfa in healthy volunteers and patients with ulcerative colitis
Gut·2023· 21 citedOpen Access
Large-scale sequencing identifies multiple genes and rare variants associated with Crohn’s disease susceptibility
Nature Genetics·2022· 175 citedOpen Access
Regulation and Role of αE Integrin and Gut Homing Integrins in Migration and Retention of Intestinal Lymphocytes during Inflammatory Bowel Disease
The Journal of Immunology·2021· 70 citedOpen Access
Oral Ferric Maltol Does Not Adversely Affect the Intestinal Microbiome of Patients or Mice, but Ferrous Sulphate Does
Nutrients·2021· 16 citedOpen Access
Oral Ferric Maltol Does Not Adversely Affect the Intestinal Microbiome of Patients or Mice, but Ferrous Sulphate Does
2021
Sequencing of over 100,000 individuals identifies multiple genes and rare variants associated with Crohns disease susceptibility
2021· 11 citedOpen Access
O13 Regulation and role of alphaE integrin in migration and retention of lymphocytes in intestinal mucosa
2021Open Access
O8 Randomised controlled trial of antibiotic/hydroxychloroquine combination versus standard budesonide in active Crohn’s disease (APRICOT)
2021
The Impact of<i>NOD2</i>Genetic Variants on the Gut Mycobiota in Crohn’s Disease Patients in Remission and in Individuals Without Gastrointestinal Inflammation
Journal of Crohn s and Colitis·2020· 41 citedOpen Access
Randomized Trial of Ciprofloxacin Doxycycline and Hydroxychloroquine Versus Budesonide in Active Crohn’s Disease
Digestive Diseases and Sciences·2020· 14 citedOpen Access
Tu1861 A RANDOMIZED, OBSERVER-BLINDED PHASE IB MULTIPLE, ASCENDING DOSE STUDY OF UTTR1147A, AN IL-22FC FUSION PROTEIN, IN HEALTHY VOLUNTEERS AND ULCERATIVE COLITIS PATIENTS.
Gastroenterology·2020
The prevention and management of Crohn’s disease postoperative recurrence: results from the Y-ECCO/ClinCom 2019 Survey
European Journal of Gastroenterology & Hepatology·2020· 11 citedOpen Access
P420 A randomised, observer-blinded phase Ib multiple, ascending dose study of UTTR1147A, an IL-22Fc fusion protein, in healthy volunteers and ulcerative colitis patients
Journal of Crohn s and Colitis·2020· 8 citedOpen Access
Diagnosis and Outcome of Oesophageal Crohn’s Disease
Journal of Crohn s and Colitis·2019· 12 citedOpen Access
HLA-DQA1*05 Carriage Associated With Development of Anti-Drug Antibodies to Infliximab and Adalimumab in Patients With Crohn’s Disease
Gastroenterology·2019· 385 citedOpen Access
PTH-102 Ferric maltol, unlike ferrous sulphate, does not adversely affect the intestinal microbiome
2019· 1 citedOpen Access
Index
2019
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Frequent Co-authors

Miles Parkes(27), Natalie J. Prescott(23), Christopher G. Mathew(23), Charlie W. Lees(21), Tariq Ahmad(18), Jeffrey C. Barrett(18), Jeremy Sanderson(17), Jack Satsangi(17), Carl A. Anderson(15), Christopher A Lamb(15), James Lee(14), Mark Tremelling(13), Sheila Fisher(12), Cathryn M. Lewis(12), Stefan Schreiber(11), Nicholas A. Kennedy(11), Alastair Forbes(10), Peter M. Irving(10), Craig Mowat(9), Clive M. Onnie(9)