Timothy L. Mosbruger

Children's Hospital of Philadelphia — United States

Immunology and Microbiology · Life Sciences

27h-index4.6kcitations88works0.72yr avg
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Research Topics

T-cell and B-cell Immunology(19), Immune Cell Function and Interaction(15), Renal Transplantation Outcomes and Treatments(12), Cancer Genomics and Diagnostics(9), Hepatitis C virus research(8)

Publications88 total

Multi-omics Differential Inference for Functional Interpretation (MoDIFI): A Statistical Framework to Prioritize Cell Lines for Neurodevelopmental Variants
2026Open Access
The complete haplotypic characterization of the swine MHC using Oxford Nanopore Technologiesrsquo; (ONT) adaptive sampling and sequencing. Optimizing the swine xenotransplantation model
Human Immunology·2025
Both Low Eplet Mismatch and Low Indirect T-Cell Recognition Scores Are Strong Prognosticators of Reduced Alloimmune Rejection in Pediatric Kidney Transplants
American Journal of Transplantation·2025
Haplotypic resolution of the challenging genomic regions of MHC and KIR using a combination of targeted sequencing and a novel assembly pipeline
Nucleic Acids Research·2025Open Access
Targeted and complete genomic sequencing of the major histocompatibility complex in haplotypic form of individual heterozygous samples
Genome Research·2024· 1 citedOpen Access
Machine Learning Insights into HLA Noncoding Sequence Mismatches and Their Impact on DPB1 Matching in Hematopoietic Cell Transplantation
2024Open Access
Comparison of alloimmune risk stratification method for kidney transplants: Correlation with outcomes from a single center pediatric transplant program
Human Immunology·2024
Non-coding mismatches in HLA Class I genes in the presence of DPB1 mismatches predict worse outcomes in hematopoietic cell transplantation
Human Immunology·2024
The Impact of Patterns in Linkage Disequilibrium and Sequencing Quality on the Imprint of Balancing Selection
Genome Biology and Evolution·2024· 5 citedOpen Access
O32 Bioinformatic segregation of chimeric libraries enables accurate donor HLA typing from allograft biopsies by ONT
Human Immunology·2023
O23 NGS HLA typing reveals low-level maternal T cell engraftment through the detection of an unexpected DRB4
Human Immunology·2023
Supplemental Methods and Supplemental Table from Discordant Haplotype Sequencing Identifies Functional Variants at the 2q33 Breast Cancer Risk Locus
2023Open Access
Supplemental Figure Legend from Discordant Haplotype Sequencing Identifies Functional Variants at the 2q33 Breast Cancer Risk Locus
2023Open Access
Data from Discordant Haplotype Sequencing Identifies Functional Variants at the 2q33 Breast Cancer Risk Locus
2023Open Access
Data from Discordant Haplotype Sequencing Identifies Functional Variants at the 2q33 Breast Cancer Risk Locus
2023Open Access
Supplemental Figure from Discordant Haplotype Sequencing Identifies Functional Variants at the 2q33 Breast Cancer Risk Locus
2023Open Access
Supplemental Figure Legend from Discordant Haplotype Sequencing Identifies Functional Variants at the 2q33 Breast Cancer Risk Locus
2023Open Access
Supplemental Methods and Supplemental Table from Discordant Haplotype Sequencing Identifies Functional Variants at the 2q33 Breast Cancer Risk Locus
2023Open Access
Supplemental Figure from Discordant Haplotype Sequencing Identifies Functional Variants at the 2q33 Breast Cancer Risk Locus
2023Open Access
Genomic characterization of <scp>HLA</scp> class I and class <scp>II</scp> genes in ethnically diverse <scp>sub‐Saharan</scp> African populations: A report on novel <scp>HLA</scp> alleles
HLA·2023· 7 citedOpen Access
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Frequent Co-authors

Jamie L. Duke(14), Dimitri Monos(13), Deborah Ferriola(11), David L. Thomas(9), Nikolaos Tairis(8), June L. Round(6), Ryan M. O’Connell(6), Amalia Dinou(6), Tristan J. Hayeck(6), Ruozhen Hu(5), Marah C. Runtsch(5), Andrea L. Cox(5), Stuart C. Ray(5), Chloe L. Thio(5), Georgios Damianos(5), Taishan Hu(5), Margaret Alexander(4), Jacquie Astemborski(4), Jared Wallace(4), Mahdi Sarmady(4)