Rosemary C. McFall

Biochemistry, Genetics and Molecular Biology · Life Sciences

17h-index1.1kcitations31works0.02yr avg
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Research Topics

Angiogenesis and VEGF in Cancer(10), HER2/EGFR in Cancer Research(8), Cancer Treatment and Pharmacology(8), Cancer, Hypoxia, and Metabolism(5), Quinazolinone synthesis and applications(4)

Publications31 total

Data from Identification of biomarkers for tumor endothelial cell proliferation through gene expression profiling
2023Open Access
Supplementary Table S1 from Identification of biomarkers for tumor endothelial cell proliferation through gene expression profiling
2023Open Access
Supplementary Table S1 from Identification of biomarkers for tumor endothelial cell proliferation through gene expression profiling
2023Open Access
Data from Identification of biomarkers for tumor endothelial cell proliferation through gene expression profiling
2023Open Access
Immunohistochemical Detection of Antitumor, Antimetastasis, and Antiangiogenesis Effects of a Vascular Endothelial Growth Factor Receptor 2 Kinase Inhibitor in an Orthotopic Breast Cancer Metastasis Model
Journal of Histotechnology·2010· 1 cited
Identification of biomarkers for tumor endothelial cell proliferation through gene expression profiling
Molecular Cancer Therapeutics·2005· 28 cited
Potent <i>N</i>-(1,3-Thiazol-2-yl)pyridin-2-amine Vascular Endothelial Growth Factor Receptor Tyrosine Kinase Inhibitors with Excellent Pharmacokinetics and Low Affinity for the hERG Ion Channel
Journal of Medicinal Chemistry·2004· 60 citedOpen Access
The discovery of N-(1,3-thiazol-2-yl)pyridin-2-amines as potent inhibitors of KDR kinase
Bioorganic & Medicinal Chemistry Letters·2004· 36 citedOpen Access
Property-Based Design of KDR Kinase Inhibitors
Current Medicinal Chemistry·2004· 35 cited
Optimization of the indolyl quinolinone class of KDR (VEGFR-2) kinase inhibitors
Bioorganic & Medicinal Chemistry Letters·2003· 52 citedOpen Access
Development of 3-methylpyridin-2-yl-aminothiazole inhibitors of the VEGF receptor
Abstracts of Papers American Chemical Society·2003
2,4‐Disubstituted Pyrimidines: A Novel Class of KDR Kinase Inhibitors.
ChemInform·2003· 1 cited
Discovery and evaluation of 3-(5-Thien-3-ylpyridin-3-yl)-1H-indoles as a novel class of KDR kinase inhibitors
Bioorganic & Medicinal Chemistry Letters·2003· 15 citedOpen Access
Design and synthesis of 1,5-diarylbenzimidazoles as inhibitors of the VEGF-receptor KDR
Bioorganic & Medicinal Chemistry Letters·2003· 18 citedOpen Access
2,4-Disubstituted pyrimidines: A novel class of KDR kinase inhibitors
Bioorganic & Medicinal Chemistry Letters·2003· 28 citedOpen Access
Optimization of a pyrazolo[1,5-a]pyrimidine class of KDR kinase inhibitors: improvements in physical properties enhance cellular activity and pharmacokinetics
Bioorganic & Medicinal Chemistry Letters·2002· 87 citedOpen Access
Synthesis and Initial SAR Studies of 3,6-Disubstituted Pyrazolo[1,5-a]pyrimidines: A New Class of KDR Kinase Inhibitors
Bioorganic & Medicinal Chemistry Letters·2002· 112 citedOpen Access
Effects of L-749,329, an ET<sub>A</sub>/ET<sub>B</sub>Endothelin Receptor Antagonist, in a Porcine Coronary Artery Injury Model of Vascular Restenosis
Circulation·2001· 10 citedOpen Access
Smooth muscle cells isolated from the neointima after vascular injury exhibit altered responses to platelet-derived growth factor and other stimuli
Journal of Cellular Physiology·1996· 33 cited
Effects of Subtype-Selective and Balanced Angiotensin II Receptor Antagonists in a Porcine Coronary Artery Model of Vascular Restenosis
Circulation·1996· 69 cited
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Frequent Co-authors

Kenneth A. Thomas(12), Kathleen Coll(11), William R. Huckle(7), Mark T. Bilodeau(7), Nancy E. Kohl(7), Keith Rickert(7), Laura Sepp‐Lorenzino(7), William F. Hoffman(6), Susan L. Hill(6), Mark E. Fraley(5), Randall W. Hungate(5), Ruth Z. Rutledge(5), Richard Kendall(5), Leonard D. Rodman(5), George D. Hartman(5), James S. Hardwick(5), Chunsheng Zhang(5), Elizabeth J. Koury(5), Hongyue Dai(5), Edward J. Weinstein(5)