Andrea Ghisleni

FIRC Institute of Molecular Oncology — Italy

Biochemistry, Genetics and Molecular Biology · Life Sciences

13h-index758citations32works2.82yr avg
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Research Topics

Cellular Mechanics and Interactions(17), Cardiomyopathy and Myosin Studies(12), Cardiovascular Effects of Exercise(10), Erythrocyte Function and Pathophysiology(9), Lipid Membrane Structure and Behavior(6)

Publications32 total

Biophysical and Molecular mechanisms that control active wetting and tissue fluidification in epithelial tissues
2025Open Access
Dynamic mechanisms for membrane skeleton transitions
Journal of Cell Science·2025Open Access
Load‐dependence of the activation of myosin filaments in heart muscle
The Journal of Physiology·2024· 4 citedOpen Access
Mechanically induced topological transition of spectrin regulates its distribution in the mammalian cell cortex
Nature Communications·2024· 13 citedOpen Access
Dynamic mechanisms for membrane skeleton transitions
2024Open Access
Heterogeneous spectrin organization dictates permissive plasma membrane domains for clathrin-mediated endocytosis
Biophysical Journal·2024
Mechanotransduction through membrane tension: It's all about propagation?
Current Opinion in Cell Biology·2023· 17 cited
PIP4K2B is mechanoresponsive and controls heterochromatin-driven nuclear softening through UHRF1
Nature Communications·2023· 20 citedOpen Access
Mechanically induced topological transition of spectrin regulates its distribution in the mammalian cortex
2023Open Access
Mechanically induced conformational transition of spectrin in the mammalian cell cortex
Biophysical Journal·2023· 4 cited
Mechanically induced topological transition of spectrin regulates its distribution in the mammalian cortex
2023· 5 citedOpen Access
PIP4K2B is a mechanosensor and induces heterochromatin-driven nuclear softening through UHRF1
2022· 1 citedOpen Access
Cooling intact and demembranated trabeculae from rat heart releases myosin motors from their inhibited conformation
The Journal of General Physiology·2022· 21 citedOpen Access
Myopalladin knockout mice develop cardiac dilation and show a maladaptive response to mechanical pressure overload
eLife·2021· 26 citedOpen Access
Adaptive mechanoproperties mediated by the formin FMN1 characterize glioblastoma fitness for invasion
Developmental Cell·2021· 27 citedOpen Access
Author response: Myopalladin knockout mice develop cardiac dilation and show a maladaptive response to mechanical pressure overload
2021· 1 citedOpen Access
Order from disorder in the sarcomere: FATZ forms a fuzzy but tight complex and phase-separated condensates with α-actinin
Science Advances·2021· 25 citedOpen Access
Structural Changes in the Myosin Filament Induced by Cooling Isolated Cardiac Trabeculae
Biophysical Journal·2021Open Access
Calcium Dependence of Myosin Filament Structure in Demembranated Trabeculae from Rat Heart
Biophysical Journal·2021Open Access
Complementary mesoscale dynamics of spectrin and acto-myosin shape membrane territories during mechanoresponse
Nature Communications·2020· 43 citedOpen Access
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Frequent Co-authors

Nils C. Gauthier(18), Michele Crestani(10), Paolo Maiuri(9), Mathias Gautel(7), Pascale Monzo(7), Elisabetta Brunello(6), Luca Fusi(6), So‐Jin Park‐Holohan(6), Theyencheri Narayanan(6), Malcolm Irving(6), Mayte Bonilla-Quintana(6), Padmini Rangamani(6), Jesús G. Ovejero(5), Camilla Galli(5), Qingsen Li(5), Kristina Djinović‐Carugo(4), Nikos Pinotsis(3), Július Košťan(3), Dmitri I. Svergun(3), Giorgio Scita(3)