Eric D. Siggia

Rockefeller University — United States

Engineering · Physical Sciences

93h-index41.7kcitations250works9.22yr avg
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Research Topics

Fluid Dynamics and Turbulent Flows(51), Pluripotent Stem Cells Research(32), Gene Regulatory Network Analysis(28), Genomics and Chromatin Dynamics(23), RNA and protein synthesis mechanisms(19)

Publications250 total

Reconstructing Waddington’s landscape from data
Proceedings of the National Academy of Sciences·2025· 2 citedOpen Access
Reconstructing Waddington's Landscape from Data
2025· 2 citedOpen Access
Quantitative guiding of developmental cell fate transitions using a dynamical landscape model
2024· 6 citedOpen Access
Mouse neural tube organoids self-organize floorplate through BMP-mediated cluster competition
Developmental Cell·2024· 22 citedOpen Access
A geometrical model of cell fate specification in the mouse blastocyst
Development·2024· 14 citedOpen Access
A geometrical model of cell fate specification in the mouse blastocyst
2023· 2 citedOpen Access
Neural tube organoids self-organise floorplate through BMP-mediated cluster competition
2023· 2 citedOpen Access
A geometrical perspective on development
Development Growth & Differentiation·2023· 20 citedOpen Access
A geometrical perspective on development
arXiv (Cornell University)·2023Open Access
Deep-learning analysis of micropattern-based organoids enables high-throughput drug screening of Huntington’s disease models
Cell Reports Methods·2022· 34 citedOpen Access
Mechanisms underlying WNT-mediated priming of human embryonic stem cells
Development·2022· 16 citedOpen Access
In vitro attachment and symmetry breaking of a human embryo model assembled from primed embryonic stem cells
Cell stem cell·2022· 54 citedOpen Access
Mechanical regulation of early vertebrate embryogenesis
Nature Reviews Molecular Cell Biology·2021· 118 cited
Human neural tube morphogenesis in vitro by geometric constraints
Nature·2021· 232 citedOpen Access
Statistically derived geometrical landscapes capture principles of decision-making dynamics during cell fate transitions
Cell Systems·2021· 138 citedOpen Access
Geometry of gene regulatory dynamics
Proceedings of the National Academy of Sciences·2021· 3 citedOpen Access
Self-organized morphogenesis of a human neural tube <i>in vitro</i> by geometric constraints
2021· 4 cited
A landscape model for cell fate decisions during mesoendoderm differentiation in C. elegans based on Wnt dynamics
2021Open Access
Differential compartmentalization of BMP4/NOGGIN requires NOGGIN trans-epithelial transport
Developmental Cell·2021· 20 citedOpen Access
A method to recapitulate early embryonic spatial patterning in human embryonic stem cells v1
2021Open Access
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Frequent Co-authors

Boris I. Shraiman(7), John F. Presley(6), John F. Marko(5), Jennifer Lippincott‐Schwartz(5), Ali H. Brivanlou(4), Jan Ellenberg(4), Bertrand I. Halperin(4), Carolyn L. Smith(3), Stellan Östlund(3), D.A.J. Rand(3), Kristien J.M. Zaal(3), Nelson B. Cole(3), Michael B. Elowitz(2), Peter S. Swain(2), Aryeh Warmflash(2), Fred Etoc(2), Jorge E. Moreira(2), Harmen J. Bussemaker(2), Hao Li(2), Magdalena Zernicka‐Goetz(2)