Ikuo Imazeki

Medicine · Health Sciences

13h-index966citations22works0.02yr avg
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Research Topics

Vitamin D Research Studies(7), Parathyroid Disorders and Treatments(7), Immunotherapy and Immune Responses(4), Computational Drug Discovery Methods(3), Animal testing and alternatives(3)

Publications22 total

Improvement of impaired calcium and skeletal homeostasis in vitamin D receptor knockout mice by a high dose of calcitriol and maxacalcitol
Bone·2009· 12 cited
Highly concentrated calcitriol and its analogues induce apoptosis of parathyroid cells and regression of the hyperplastic gland--study in rats
Nephrology Dialysis Transplantation·2007· 13 citedOpen Access
Binding of highly concentrated maxacalcitol to the nuclear vitamin D receptors of parathyroid cells
Nephrology Dialysis Transplantation·2007· 6 citedOpen Access
Possibility of vitamin D receptor independent Ca regulation of maxacalcitol
Nephrology Dialysis Transplantation·2007
Direct maxacalcitol injection into hyperplastic parathyroids improves skeletal changes in secondary hyperparathyroidism
Kidney International·2006· 13 citedOpen Access
1α,25‐Dihydroxyvitamin D3 downmodulates the functional differentiation of Th1 cytokine‐conditioned bone marrow‐derived dendritic cells beneficial for cytotoxic T lymphocyte generation
Cancer Science·2006· 24 citedOpen Access
Immunomodulating effect of vitamin D3 derivatives on type-1 cellular immunity
Biomedical Research·2006· 81 citedOpen Access
Severe hyperparathyroidism with bone abnormalities and metastatic calcification in rats with adenine-induced uraemia
Nephrology Dialysis Transplantation·2005· 106 citedOpen Access
Immunosteroid as a regulator for Th1/Th2 balance: Its possible role in autoimmune diseases
Autoimmunity·2005· 61 cited
Biochemical and Cellular Effects of Direct Maxacalcitol Injection into Parathyroid Gland in Uremic Rats
Journal of the American Society of Nephrology·2004· 41 cited
Maxacalcitol, a medicine for secondary hyperparathyroidism (2°HPT)
Folia Pharmacologica Japonica·2003· 2 citedOpen Access
Long-term production of erythropoietin after electroporation-mediated transfer of plasmid DNA into the muscles of normal and uremic rats
Gene Therapy·2001· 76 cited
Continuous Erythropoietin Delivery by Muscle-Targeted Gene Transfer Using <i>in Vivo</i> Electroporation
Human Gene Therapy·2000· 81 cited
IL-6 functions in cynomolgus monkeys blocked by a humanized antibody to human IL-6 receptor
International Journal of Immunopharmacology·1998· 16 cited
In vivo blocking effects of a humanized antibody to human interleukin-6 receptor on interleukin-6 function in primates.
PubMed·1998· 11 cited
Validation Study on Five Cytotoxicity Assays by JSAAE - VII. Details of the MTT Assay
1998· 4 cited
Validation Study on Five Cytotoxicity Assays by JSAAE - VIII. Details of the Neutral Red Uptake A
1998· 4 cited
Validation Study on Five Cytotoxicity Assays by JSAAE I. Overview of the Study and Analyses of Variations of ED50 Values
1998· 1 cited
Safety and kinetic properties of a humanized antibody to human interleukin-6 receptor in healthy non-human primates
Toxicology·1997· 3 cited
Thrombopoietic activity of human interleukin‐6
FEBS Letters·1990· 31 citedOpen Access
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Frequent Co-authors

Kazuhiro Shiizaki(6), Ikuji Hatamura(6), Tadao Akizawa(6), Shigeo Negi(5), Fumie Saji(4), Takeshi Sakaguchi(4), Yoshiyuki Moriguchi(3), Junko Matsuzaki(3), Takashi Nishimura(3), Hirofumi Shinkura(3), Tadao Ohno(3), Masato Hatao(3), Makoto Hayashi(3), Mayako Kato(3), Minako Mori(3), Keiya Nakajima(3), Hiroshi Ono(3), Kaoru Saijo(3), Tetsuji Sasaki(3), Xinhai Wang(3)