K.L. Britton

University of Sheffield — United Kingdom

Materials Science · Physical Sciences

24h-index2.6kcitations60works0.02yr avg
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Research Topics

Enzyme Structure and Function(43), Protein Structure and Dynamics(20), Amino Acid Enzymes and Metabolism(20), GABA and Rice Research(15), Biochemical and Molecular Research(11)

Publications60 total

Mirror‐Image Packing Provides a Molecular Basis for the Nanomolar Equipotency of Enantiomers of an Experimental Herbicide
Angewandte Chemie·2016· 2 citedOpen Access
Mirror‐Image Packing Provides a Molecular Basis for the Nanomolar Equipotency of Enantiomers of an Experimental Herbicide
Angewandte Chemie International Edition·2016· 17 citedOpen Access
A. thaliana IGPD2 in complex with the triazole-phosphonate inhibitor, (S)-C348, to 1.1A resolution
2015
Crystal structure of IGPD from Pyrococcus furiosus in complex with (S)-C348
2015
Crystal Structures Reveal that the Reaction Mechanism of Imidazoleglycerol-Phosphate Dehydratase Is Controlled by Switching Mn(II) Coordination
Structure·2015· 35 citedOpen Access
The structure of wt A. thaliana IGPD2 in complex with Mn2+ and phosphate
2014
The structure of wt A. thaliana IGPD2 in complex with Mn2+ and formate at 1.3A resolution
2014
The form B structure of an E21Q catalytic mutant of A. thaliana IGPD2 in complex with Mn2+ and its substrate, 2R3S-IGP, to 1.41 A resolution
2013
The form A structure of an E21Q catalytic mutant of A. thaliana IGPD2 in complex with Mn2+ and a mixture of its substrate, 2R3S-IGP, and an inhibitor, 2S3S-IGP, to 1.12 A resolution
2013
The structure of wt A. thaliana IGPD2 in complex with Mn2+ and 1,2,4-triazole at 1.3 A resolution
2013
Active site dynamics in the zinc-dependent medium chain alcohol dehydrogenase superfamily
Proceedings of the National Academy of Sciences·2009· 72 citedOpen Access
Haloferax mediterranei glucose dehydrogenase in complex with NADPH and Zn.
2008
Haloferax mediterranei glucose dehydrogenase in complex with NADP, Zn and glucose.
2008
Haloferax mediterranei glucose dehydrogenase in complex with NADP, Zn and gluconolactone.
2008
Analysis of protein solvent interactions in glucose dehydrogenase from the extreme halophile <i>Haloferax mediterranei</i>
Proceedings of the National Academy of Sciences·2006· 136 citedOpen Access
Crystal structure of glucose dehydrogenase from Haloferax mediterranei
2005
Crystal structure of D38C glucose dehydrogenase mutant from Haloferax mediterranei
2005
Crystallization and preliminary X-ray analysis of binary and ternary complexes of<i>Haloferax mediterranei</i>glucose dehydrogenase
Acta Crystallographica Section F Structural Biology and Crystallization Communications·2005· 8 citedOpen Access
Kinetic analysis of phenylalanine dehydrogenase mutants designed for aliphatic amino acid dehydrogenase activity with guidance from homology‐based modelling
European Journal of Biochemistry·2003· 19 cited
Single Amino Acid Substitution in <i>Bacillus sphaericus</i> Phenylalanine Dehydrogenase Dramatically Increases Its Discrimination between Phenylalanine and Tyrosine Substrates
Biochemistry·2002· 35 cited
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Frequent Co-authors

David W. Rice(38), Patrick J. Baker(36), Timothy J. Stillman(28), Paul C. Engel(20), Svetlana E. Sedelnikova(9), Alessandra Pasquo(8), Kitty S. P. Yip(8), Martin Fisher(7), Marı́a-José Bonete(7), Juan Ferrer(7), Carmen Pire(7), Julia Esclapez(7), C. Bisson(7), H. Fiona Rodgers(7), D.W. Rice(7), R Scandurra(6), Yasuhisa Asano(6), T.C. Eadsforth(6), Tim Hawkes(6), Frank T. Robb(5)