Colin W. Pouton

Centre hospitalier de l'Université Laval — Canada

Biochemistry, Genetics and Molecular Biology · Life Sciences

60h-index18.5kcitations299works10.12yr avg
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Research Topics

RNA Interference and Gene Delivery(53), Drug Solubulity and Delivery Systems(52), Pluripotent Stem Cells Research(34), Virus-based gene therapy research(26), Advanced biosensing and bioanalysis techniques(23)

Publications299 total

Structuring of lipid nanoparticle mRNA formulations at acidic and neutral pH: X-ray scattering and molecular dynamics studies
Molecular Therapy — Methods & Clinical Development·2025· 2 citedOpen Access
High-stability, clamp-free soluble Sarbecovirus spike trimers and their potential for pan-Sarbecovirus vaccine development
2025Open Access
Melanocortin receptors in GtoPdb v.2025.3
IUPHAR/BPS Guide to Pharmacology CITE·2025Open Access
Morphological changes induced by buffer exchange during preparation of mRNA-lipid nanoparticles occur in a stepwise manner as pH is elevated
Molecular Therapy — Methods & Clinical Development·2025· 2 citedOpen Access
A versatile antibody capture system drives specific in vivo delivery of mRNA-loaded lipid nanoparticles
Nature Nanotechnology·2025· 11 citedOpen Access
Cryo-EM structure of endogenous <i>Plasmodium falciparum</i> Pfs230 and Pfs48/45 fertilization complex
Science·2025· 8 cited
Impact of ionizable lipid type on the pharmacokinetics and biodistribution of mRNA-lipid nanoparticles after intravenous and subcutaneous injection
Journal of Controlled Release·2025· 19 citedOpen Access
Efficient mRNA delivery to resting T cells to reverse HIV latency
Nature Communications·2025· 13 citedOpen Access
Lipid-Polyhydroxyalkanoate Hybrid Nanoparticles as Sustainable Platform for mRNA delivery
European Journal of Pharmaceutics and Biopharmaceutics·2025· 5 citedOpen Access
An LNP-mRNA vaccine modulates innate cell trafficking and promotes polyfunctional Th1 CD4+ T cell responses to enhance BCG-induced protective immunity against Mycobacterium tuberculosis
EBioMedicine·2025· 11 citedOpen Access
Cryo-EM structure of endogenous <i>Plasmodium falciparum</i> Pfs230 and Pfs48/45 fertilization complex
2025· 4 citedOpen Access
Transient inhibition of type I interferon enhances CD8+ T cell stemness and vaccine protection
The Journal of Experimental Medicine·2025· 17 citedOpen Access
Influence of hydrophilic polymers on the accelerated blood clearance of mRNA lipid nanoparticles upon repeated administration
Nanoscale Horizons·2025· 1 citedOpen Access
Development of an oral vaccine delivery system for shrimp aquaculture using attenuated Listeria monocytogenes
Aquaculture·2024· 1 cited
mRNA vaccines encoding membrane-anchored RBDs of SARS-CoV-2 mutants induce strong humoral responses and can overcome immune imprinting
Molecular Therapy — Methods & Clinical Development·2024· 2 citedOpen Access
Conversion of vaccines from low to high immunogenicity by antibodies with epitope complementarity
Immunity·2024· 26 cited
Replacing poly(ethylene glycol) with RAFT lipopolymers in mRNA lipid nanoparticle systems for effective gene delivery
International Journal of Pharmaceutics·2024· 11 citedOpen Access
Therapeutic applications of cell engineering using mRNA technology
Trends in biotechnology·2024· 5 cited
A Versatile Antibody Capture System that Drives Precise <i>In Viv</i> o Delivery of mRNA loaded Lipid Nanoparticles and Enhances Gene Expression
2024· 3 citedOpen Access
A lipid nanoparticle-mRNA vaccine provides potent immunogenicity and protection against <i>Mycobacterium tuberculosis</i>
2024· 5 citedOpen Access
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Frequent Co-authors

Christopher J. H. Porter(14), Hywel D. Williams(9), William N. Charman(6), Hassan Benameur(6), John M. Haynes(5), Natalie L. Trevaskis(4), Dallas B. Warren(4), Anette Müllertz(4), Gregory W. Moseley(4), David A. Jans(4), Jean F. Cuiné(3), Leonard W. Seymour(3), David A. Elliott(3), Andrew G. Elefanty(3), Edouard G. Stanley(3), Philip Sassene(3), Karen Kleberg(3), Marilyn Calderone(3), Vincent Jannin(3), Annabel Igonin(3)