Alessandra Esposito

Scuola Superiore Meridionale — Italy

Medicine · Health Sciences

10h-index1.4kcitations17works9.32yr avg
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Research Topics

Autophagy in Disease and Therapy(8), Cellular transport and secretion(8), Calcium signaling and nucleotide metabolism(6), Lysosomal Storage Disorders Research(5), Renal cell carcinoma treatment(2)

Publications17 total

Structural basis for mTORC1 activation on the lysosomal membrane
Nature·2025· 10 citedOpen Access
Structural basis for growth factor and nutrient signal integration on the lysosomal membrane by mTORC1
2024· 3 citedOpen Access
A SPLICS reporter reveals $${{{{{\boldsymbol{\alpha }}}}}}$$-synuclein regulation of lysosome-mitochondria contacts which affects TFEB nuclear translocation
Nature Communications·2024· 15 citedOpen Access
TFEB and TFE3 control glucose homeostasis by regulating insulin gene expression
The EMBO Journal·2023· 15 citedOpen Access
EDITORIAL COMMENT
Urology·2023
Loss of the batten disease protein CLN3 leads to mis-trafficking of M6PR and defective autophagic-lysosomal reformation
Nature Communications·2023· 44 citedOpen Access
Structure of the lysosomal mTORC1–TFEB–Rag–Ragulator megacomplex
Nature·2023· 166 citedOpen Access
Author Correction: LC3 lipidation is essential for TFEB activation during the lysosomal damage response to kidney injury
Nature Cell Biology·2022· 4 citedOpen Access
Structural basis for mTORC1-dependent regulation of the lysosomal and autophagic transcription factor TFEB
2022Open Access
Current methods to analyze lysosome morphology, positioning, motility and function
Traffic·2022· 161 citedOpen Access
Fluoxetine ameliorates mucopolysaccharidosis type IIIA
Molecular Therapy·2022· 27 citedOpen Access
Repurposing of tamoxifen ameliorates CLN3 and CLN7 disease phenotype
EMBO Molecular Medicine·2021· 44 citedOpen Access
LC3 lipidation is essential for TFEB activation during the lysosomal damage response to kidney injury
Nature Cell Biology·2020· 224 cited
A substrate-specific mTORC1 pathway underlies Birt–Hogg–Dubé syndrome
Nature·2020· 302 citedOpen Access
骨折修復におけるPrx1発現骨格細胞とPrx1発現の役割【JST・京大機械翻訳】
2020
mTOR-dependent phosphorylation controls TFEB nuclear export
Nature Communications·2018· 381 citedOpen Access
mTOR-dependent phosphorylation controls TFEB nuclear export
2018· 6 citedOpen Access

Frequent Co-authors

Gennaro Napolitano(15), Andrea Ballabio(12), Jlenia Monfregola(8), Diego L. Medina(6), Chiara Di Malta(4), Zhicheng Cui(4), James H. Hurley(4), Maria Matarese(3), Valerio Benedetti(3), Mariana E. G. de Araújo(3), Lukas A. Huber(3), Sandro Montefusco(3), Heejun Choi(2), Jennifer Lippincott‐Schwartz(2), Marcella Cesana(2), Alessia Calcagnì(2), Shuhei Nakamura(2), Saki Shigeyama(2), Satoshi Minami(2), Takayuki Shima(2)