Alexandra Kupke

Philipps University of Marburg — Germany

Medicine · Health Sciences

20h-index4.9kcitations43works3.42yr avg
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Research Topics

SARS-CoV-2 and COVID-19 Research(31), Animal Virus Infections Studies(13), Viral Infections and Outbreaks Research(12), Viral gastroenteritis research and epidemiology(8), COVID-19 Clinical Research Studies(7)

Publications42 total

Side-by-side evaluation of two mouse models for Crimean-Congo Hemorrhagic Fever Virus infection
2025Open Access
Differential efficacy of first licensed western vaccines protecting without immunopathogenesis Wuhan-1-challenged hamsters from severe COVID-19
npj Vaccines·2025Open Access
Rapid Development of Modified Vaccinia Virus Ankara (MVA)-Based Vaccine Candidates Against Marburg Virus Suitable for Clinical Use in Humans
Vaccines·2024· 4 citedOpen Access
Organotypic brain slices as a model to study the neurotropism of the highly pathogenic Nipah and Ebola viruses
Journal of General Virology·2024· 2 citedOpen Access
Susceptibility to SARS-CoV-2 infection in a T2-biased experimental asthma model
2024
Hamster Model of Severe COVID-19 Demonstrates Differential Efficacy of first Licensed Western Vaccines in the Absence of Immunopathogenesis
2024Open Access
T-bet+ B cells are activated by and control endogenous retroviruses through TLR-dependent mechanisms
Nature Communications·2024· 18 citedOpen Access
Short- and Long-Interval Prime-Boost Vaccination with the Candidate Vaccines MVA-SARS-2-ST and MVA-SARS-2-S Induces Comparable Humoral and Cell-Mediated Immunity in Mice
Viruses·2023· 8 citedOpen Access
Self-amplifying RNA vaccine protects mice against lethal Ebola virus infection
Molecular Therapy·2022· 18 citedOpen Access
Stabilized recombinant SARS-CoV-2 spike antigen enhances vaccine immunogenicity and protective capacity
Journal of Clinical Investigation·2022· 32 citedOpen Access
Vaccine-associated enhanced respiratory pathology in COVID-19 hamsters after TH2-biased immunization
Cell Reports·2022· 52 citedOpen Access
Increased neutralization and IgG epitope identification after MVA-MERS-S booster vaccination against Middle East respiratory syndrome
Nature Communications·2022· 20 citedOpen Access
Protective CD8+ T Cell Response Induced by Modified Vaccinia Virus Ankara Delivering Ebola Virus Nucleoprotein
Vaccines·2022· 12 citedOpen Access
Cyclosporin A Reveals Potent Antiviral Effects in Preclinical Models of SARS-CoV-2 Infection
American Journal of Respiratory and Critical Care Medicine·2022· 17 citedOpen Access
Increased neutralization and IgG epitope identification after MVA-MERS-S booster vaccination against Middle East respiratory syndrome
2022
In contrast to T <sub>H</sub> 2-biased approaches, T <sub>H</sub> 1 COVID-19 vaccines protect Syrian hamsters from severe disease in the absence of dexamethasone-treatable vaccine-associated enhanced respiratory pathology
2021· 1 citedOpen Access
Post-viral effects of COVID-19 in the olfactory system and their implications
The Lancet Neurology·2021· 184 citedOpen Access
Intranasal Administration of a Monoclonal Neutralizing Antibody Protects Mice against SARS-CoV-2 Infection
Viruses·2021· 55 citedOpen Access
Immunogenicity and efficacy of the COVID-19 candidate vector vaccine MVA-SARS-2-S in preclinical vaccination
Proceedings of the National Academy of Sciences·2021· 96 citedOpen Access
Intranasal administration of a monoclonal neutralizing antibody protects mice against SARS-CoV-2 infection
2021· 13 citedOpen Access
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Frequent Co-authors

Stephan Becker(22), Cornelius Rohde(17), Sandro Halwe(14), Asisa Volz(10), Gerd Sutter(10), Lucie Sauerhering(10), Verena Krähling(9), Markus Eickmann(9), Michelle Gellhorn Serra(9), Jörg Schmidt(8), Sylvia Jany(7), Alina Tscherne(7), Georgia Kalodimou(7), Florian Klein(6), Astrid Freudenstein(6), Michael Klüver(6), Christoph Kreer(5), Matthias Zehner(5), Kanika Vanshylla(5), Manuel Koch(5)