J. Carlos Menéndez

Universidad Complutense de Madrid — Spain

Chemistry · Physical Sciences

47h-index11.2kcitations597works4.02yr avg
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Research Topics

Multicomponent Synthesis of Heterocycles(104), Synthesis and Biological Evaluation(93), Chemical Synthesis and Analysis(71), Bioactive Compounds and Antitumor Agents(67), Synthesis and Reactions of Organic Compounds(67)

Publications597 total

Mechanochemical Reductive Amination of Aldehydes and Ketones: Solid-State Synthesis of the Antiparkinsonian Drugs Rasagiline and Safinamide
ACS Sustainable Chemistry & Engineering·2025
2-Styrylquinolines with Push-Pull Architectures as Sensors for β-Amyloid Aggregation with Theranostic Properties
International Journal of Molecular Sciences·2025Open Access
Regioselective N-2 Alkylation of Tetrazoles with Phenacyl Halides under Mechanochemical Conditions and Its Application to a Solid-State Synthesis of the Antiepileptic Drug Cenobamate
ACS Sustainable Chemistry & Engineering·2025· 1 citedOpen Access
Drug design, green synthesis, in-vitro antibacterial and antifungal activities, computational investigation, and molecular docking studies of novel spiro-indoline-pyrano-pyrimidine and pyrazolo derivatives
Journal of Molecular Structure·2025· 14 citedOpen Access
Network-Based Drug Optimization toward the Treatment of Parkinson’s Disease: NRF2, MAO-B, Oxidative Stress, and Chronic Neuroinflammation
Journal of Medicinal Chemistry·2025· 4 citedOpen Access
Sensing Reactive Oxygen and Nitrogen Species with Cyclodextrins and Their Nanostructured Systems
2025
Modulation of the KEAP1–NRF2 Pathway for the Treatment of Neurodegenerative Diseases: Rationale, Assay Methodologies, and Reference Compounds
Neuromethods·2024
Twenty-first century antiepileptic drugs. An overview of their targets and synthetic approaches
European Journal of Medicinal Chemistry·2024· 20 citedOpen Access
Dual Antitubercular and Antileishmanial Profiles of Quinoxaline Di-N-Oxides Containing an Amino Acidic Side Chain
Pharmaceuticals·2024· 2 citedOpen Access
Fluorimetric Detection of Insulin Misfolding by Probes Derived from Functionalized Fluorene Frameworks
Molecules·2024Open Access
Eugenol derivatives containing 1,2,3-triazole-chalcone hybrids for shikimate kinase inhibition
Journal of Saudi Chemical Society·2024· 6 citedOpen Access
Structure-Antitumor Activity Relationships of Aza- and Diaza-Anthracene-2,9,10-Triones and Their Partially Saturated Derivatives
Molecules·2024· 1 citedOpen Access
Cyclodextrin Inclusion Complexes for Improved Drug Bioavailability and Activity: Synthetic and Analytical Aspects
Pharmaceutics·2023· 143 citedOpen Access
CCDC 2261191: Experimental Crystal Structure Determination
The Cambridge Structural Database·2023Open Access
CCDC 2261188: Experimental Crystal Structure Determination
The Cambridge Structural Database·2023Open Access
CCDC 2261189: Experimental Crystal Structure Determination
The Cambridge Structural Database·2023Open Access
Rapid Assembly of Functionalized 2<i>H</i>-Chromenes and 1,2-Dihydroquinolines via Microwave-Assisted Secondary Amine-Catalyzed Cascade Annulation of 2-<i>O</i>/<i>N</i>-Propargylarylaldehydes with 2,6-Dialkylphenols
The Journal of Organic Chemistry·2023· 9 cited
Quinones as Neuroprotective Agents
Antioxidants·2023· 73 citedOpen Access
Quinolinetrione-tacrine hybrids as multi-target-directed ligands against Alzheimer's disease
Bioorganic & Medicinal Chemistry·2023· 16 citedOpen Access
m-Terphenylamines, Acting as Selective COX-1 Inhibitors, Block Microglia Inflammatory Response and Exert Neuroprotective Activity
Molecules·2023· 6 citedOpen Access
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Frequent Co-authors

Vellaisamy Sridharan(13), Mercedes Villacampa(9), Carmen Avendaño(9), Subbu Perumal(9), Verónica Estévez(4), M. Antonia Martín(4), Pilar López‐Alvarado(4), M. Teresa Ramos(4), Ángel Cores(4), Marco Leonardi(3), Matteo Staderini(3), María Laura Bolognesi(3), Michael Rajesh Stephen(3), Rafael León(3), José Clerigué(3), Kamaraj Balamurugan(3), Padmakar A. Suryavanshi(2), Perumal Yogeeswari(2), Dharmarajan Sriram(2), Paramasivan T. Perumal(2)