Ozlem Yedier-Bayram

Bahçeşehir University — Turkey

Biochemistry, Genetics and Molecular Biology · Life Sciences

7h-index270citations21works3.52yr avg
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Research Topics

Protein Degradation and Inhibitors(5), Autophagy in Disease and Therapy(4), Epigenetics and DNA Methylation(3), CRISPR and Genetic Engineering(3), Histone Deacetylase Inhibitors Research(3)

Publications21 total

Target-specific de novo design of drug candidate molecules with graph-transformer-based generative adversarial networks
Nature Machine Intelligence·2025· 1 citedOpen Access
Chromatin-focused genetic and chemical screens identify BRPF1 as a targetable vulnerability in Taxol-resistant triple-negative breast cancer
Experimental & Molecular Medicine·2025· 2 citedOpen Access
Functional Genomic Screens Reveal RBBP4 as a Key Regulator of Cell Cycle Progression in TMZ-Resistant Glioblastoma
2025Open Access
Abstract 4404: BRPF1 inhibition restores chemosensitivity in triple negative breast cancer via ribosomal pathway modulation
Cancer Research·2025
Chromatin-focused genetic and chemical screens identify BRPF1 as a targetable vulnerability in Taxol-resistant triple-negative breast cancer
2024Open Access
Exploiting epigenetic targets to overcome taxane resistance in prostate cancer
Cell Death and Disease·2024· 18 citedOpen Access
P03.10.A IDENTIFYING DNA DAMAGE RESPONSE (DDR) RELATED FACTORS ESSENTIAL FOR RADIOTHERAPY RESPONSE IN GLIOBLASTOMA USING A NOVEL CRISPR/CAS9 LIBRARY, DDRKOL
Neuro-Oncology·2023Open Access
Exploiting Epigenetic Targets to Overcome Taxane Resistance in Prostate Cancer
2023Open Access
Overcoming chemoresistance in triple negative breast cancer by bromodomain inhibition
European Journal of Cancer·2022Open Access
EPIKOL, a chromatin-focused CRISPR/Cas9-based screening platform, to identify cancer-specific epigenetic vulnerabilities
Cell Death and Disease·2022· 17 citedOpen Access
Genome-wide CRISPR screen identifies PRC2 and KMT2D-COMPASS as regulators of distinct EMT trajectories that contribute differentially to metastasis
Nature Cell Biology·2022· 122 citedOpen Access
EPIKOL, a chromatin-focused CRISPR/Cas9-based screening platform, to identify cancer-specific epigenetic vulnerabilities
2021· 8 citedOpen Access
Abstract PR05: Loss of PRC2 or KMT2D-COMPASS generates two quasi-mesenchymal cell states with distinct metastatic abilities
Cancer Research·2020
PMA functions as an autophagy inhibitor through activation of a serine threonine kinase
Sabanci University·2017
Identification of a serine-threonine kinase as a novel autophagic regulator
Sabanci University·2017
Involvement of autophagy in T cell biology.
PubMed·2017· 15 cited
Effect of Serine/Threonine Kinases on Autophagy Mechanism
Sabanci University·2016
Serum leptin, prolactin and vascular endothelial growth factor (VEGF) levels in patients with breast cancer.
PubMed·2003· 58 cited
Effect of different neoadjuvant chemotherapy regimens on locally advanced breast cancer.
PubMed·2003· 5 cited
Role of endogenous endothelin peptides in intestinal ischemia-reperfusion injury in rats
Prostaglandins Leukotrienes and Essential Fatty Acids·1998· 17 cited
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Frequent Co-authors

Tugba Bagcı-Önder(10), Nathan A. Lack(7), Tamer T. Önder(7), Hamzah Syed(7), Ali Cenk Aksu(7), Ayşe Derya Cavga(6), Ahmet Cingöz(6), Buse Cevatemre(5), Beyza Dedeoğlu(5), Ceyda Açılan(5), Martin Philpott(5), Adam P. Cribbs(5), Beril Esin(4), Seval Kılıç(4), Devrim Gözüaçık(4), Ebru Yilmaz(4), Erhan Onuk(3), Alişan Kayabölen(3), Ezgi Yağmur Kala(3), Yun Zhang(2)