Déborah Hirt

Inserm — France

Medicine · Health Sciences

28h-index2.5kcitations128works2.02yr avg
OpenAlex↗ORCID↗Google Scholar↗Lab page↗

Accepting Students?

No reports yet. Know if this professor is taking students?

Research Topics

HIV/AIDS drug development and treatment(60), HIV/AIDS Research and Interventions(37), HIV Research and Treatment(34), Antibiotics Pharmacokinetics and Efficacy(28), Pharmacological Effects and Toxicity Studies(22)

Publications128 total

Pharmacokinetics of cefotaxime and its metabolite desacetyl-cefotaxime to optimize dosing in critically ill children and children with sickle cell disease
Journal of Antimicrobial Chemotherapy·2026
Cefazolin population pharmacokinetics in children undergoing maintenance hemodialysis for kidney failure
Antimicrobial Agents and Chemotherapy·2025· 1 citedOpen Access
Cefepime exposure in prolonged or intermittent infusion in critically ill children
2025Open Access
Assessment of the steady-state drug–drug interactions between dolutegravir and ritonavir-boosted darunavir in adolescents
AIDS·2025
Improving cefazolin exposure in critically ill children using a population pharmacokinetic model
British Journal of Clinical Pharmacology·2024· 2 citedOpen Access
A rapid LC-MS/MS method for the simultaneous quantification of ivacaftor, lumacaftor, elexacaftor, tezacaftor, hexyl-methyl ivacaftor and ivacaftor carboxylate in human plasma
Journal of Pharmaceutical and Biomedical Analysis·2024· 13 cited
Improving cefazolin exposure in critically ill children using population pharmacokinetic model
2024· 1 citedOpen Access
Optimization of vigabatrin dosage in children with epileptic spasms: A population pharmacokinetic approach
British Journal of Clinical Pharmacology·2024· 1 citedOpen Access
A Rapid Lc-Ms/Ms Method for the Simultaneous Quantification of Ivacaftor, Lumacaftor, Elexacaftor, Tezacaftor, Hexyl-Methyl Ivacaftor and Ivacaftor Carboxylate in Human Plasma
SSRN Electronic Journal·2024Open Access
Simultaneous pharmacokinetic modeling of unbound and total darunavir with ritonavir in adolescents: a substudy of the SMILE trial
Antimicrobial Agents and Chemotherapy·2023· 1 citedOpen Access
Nucleoside/nucleotide reverse transcriptase inhibitor sparing regimen with once daily integrase inhibitor plus boosted darunavir is non-inferior to standard of care in virologically-suppressed children and adolescents living with HIV – Week 48 results of the randomised SMILE Penta-17-ANRS 152 clinical trial
EClinicalMedicine·2023· 14 citedOpen Access
Population pharmacokinetics of unbound and total dolutegravir concentrations in children aged 12 years and older: a PK substudy of the SMILE trial
Journal of Antimicrobial Chemotherapy·2023· 1 cited
Pharmacokinetic profile of acyclovir in a child receiving continuous kidney replacement therapy for acute liver failure
Pediatric Nephrology·2023· 4 citedOpen Access
Correction to: Beta-lactam exposure and safety in intermittent or continuous infusion in critically ill children: an observational monocenter study
European Journal of Pediatrics·2022Open Access
Beta-lactam exposure and safety in intermittent or continuous infusion in critically ill children: an observational monocenter study
European Journal of Pediatrics·2022· 6 cited
Frequencies, Modalities, Doses and Duration of Computerized Prescriptions for Sedative, Analgesic, Anesthetic and Paralytic Drugs in Neonates Requiring Intensive Care: A Prospective Pharmacoepidemiologic Cohort Study in 30 French NICUs From 2014 to 2020
Frontiers in Pharmacology·2022· 7 citedOpen Access
What babies need: accelerating access to current and novel antiretroviral drugs in neonates through pharmacokinetic studies
The Lancet HIV·2022· 20 cited
Cefepime population pharmacokinetics and dosing regimen optimization in critically ill children with different renal function
Clinical Microbiology and Infection·2022· 13 cited
Oral levofloxacin: population pharmacokinetics model and pharmacodynamics study in bone and joint infections
Journal of Antimicrobial Chemotherapy·2022· 17 cited
High nevirapine levels in breast milk and consequences in HIV-infected child when initiated on antiretroviral therapy
AIDS·2021· 2 cited
page 1 of 7Next →

Frequent Co-authors

Jean‐Marc Tréluyer(43), Saı̈k Urien(30), Sihem Benaboud(24), Naïm Bouazza(18), Frantz Foissac(16), Stéphane Blanche(14), Elisabeth Rey(12), Yi Zheng(10), Elodie Valade(8), Gabrielle Lui(8), Ghislaine Firtion(7), Inès Gana(6), Mehdi Oualha(6), Laurent Mandelbrot(6), Élise Arrivé(5), Maïlys De Sousa Mendes(5), Agathe Béranger(5), Sílvia M. Illamola(5), Didier Koumavi Ekouévi(4), Divine Avit(4)