Ruize Gao

Luxembourg Institute of Health — LU

Medicine · Health Sciences

9h-index1.9kcitations16works0.32yr avg
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Research Topics

Autophagy in Disease and Therapy(5), Hippo pathway signaling and YAP/TAZ(4), Cancer, Hypoxia, and Metabolism(3), Cancer Immunotherapy and Biomarkers(2), Ubiquitin and proteasome pathways(2)

Publications16 total

ACB1801 enhances tumor immunogenicity by targeting glycolysis/ferroptosis vulnerability and activating STAT1-signaling to overcome anti-PD-1 resistance in MSS colorectal cancer
2026Open Access
Abstract 2231: CY-101 inhibits the tumor growth and improves anti-PD-1 immunotherapy in beta-catenin-driven tumors
Cancer Research·2025
Targeting the atypical chemokine receptor 2 ( <i>Ackr2</i> ) improves the benefit of anti-PD-1 immunotherapy in melanoma mouse model
OncoImmunology·2025· 1 citedOpen Access
Abstract 4049: The beta-carboline Harmine sensitives microsatellite stable colorectal cancer mouse model to anti-PD-1 through upregulating MHC-I dependent antigen presentation machinery and improving the infiltration of CD8 T cells into the tumor microenvironment
Cancer Research·2024
Protocol to screen for Sorafenib resistance regulators using pooled lentiviral shRNA library and a Sorafenib-resistant hepatocellular carcinoma cell model
STAR Protocols·2023· 7 citedOpen Access
Hypoxia features as potential indicators in prognosis, immunotherapy and drug screening in hepatocellular carcinoma patients
Translational Cancer Research·2022· 1 citedOpen Access
YAP/TAZ and ATF4 drive resistance to Sorafenib in hepatocellular carcinoma by preventing ferroptosis
EMBO Molecular Medicine·2021· 468 citedOpen Access
USP29-mediated HIF1α stabilization is associated with Sorafenib resistance of hepatocellular carcinoma cells by upregulating glycolysis
Oncogenesis·2021· 57 citedOpen Access
LATS1 but not LATS2 represses autophagy by a kinase-independent scaffold function
Nature Communications·2019· 68 citedOpen Access
The SIAH2-NRF1 axis spatially regulates tumor microenvironment remodeling for tumor progression
Nature Communications·2019· 88 citedOpen Access
Regulation of mATG9 trafficking by Src- and ULK1-mediated phosphorylation in basal and starvation-induced autophagy
Cell Research·2016· 201 citedOpen Access
Mitophagy receptor FUNDC1 regulates mitochondrial dynamics and mitophagy
Autophagy·2016· 537 citedOpen Access
Zyxin-Siah2–Lats2 axis mediates cooperation between Hippo and TGF-β signalling pathways
Nature Communications·2016· 118 citedOpen Access
Parkin promotes proteasomal degradation of p62: implication of selective vulnerability of neuronal cells in the pathogenesis of Parkinson’s disease
Protein & Cell·2016· 102 citedOpen Access
Mitophagy receptor FUNDC1 regulates mitochondrial dynamics and mitophagy
Figshare·2016Open Access
Hypoxia regulates Hippo signalling through the SIAH2 ubiquitin E3 ligase
Nature Cell Biology·2014· 279 cited

Frequent Co-authors

Quan Chen(6), Yushan Zhu(5), Gerhard Christofori(4), Fengyuan Tang(4), Chenglong Mu(4), Kris Van Moer(4), Ravi Kiran Reddy Kalathur(3), David Buechel(3), Salvatore Piscuoglio(3), Biao Ma(3), Hongcheng Cheng(3), Linbo Chen(3), Bassam Janji(3), Margaux Poussard(3), Chongzhuo Zhu(2), Mairene Coto‐Llerena(2), Caner Ercan(2), Shuang Song(2), Ling Chen(2), Changqian Zhou(2)