Weifang Tang

China Pharmaceutical University — China

Chemistry · Physical Sciences

21h-index1.2kcitations68works16.02yr avg
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Research Topics

N-Heterocyclic Carbenes in Organic and Inorganic Chemistry(20), Catalytic C–H Functionalization Methods(16), Catalytic Cross-Coupling Reactions(16), Synthetic Organic Chemistry Methods(10), Melanoma and MAPK Pathways(8)

Publications68 total

Design, Synthesis, and Biological Evaluation of a Novel NIK Inhibitor with Anti-Inflammatory and Hepatoprotective Effects for Sepsis Treatment
Journal of Medicinal Chemistry·2024· 11 citedOpen Access
Photochemical selective difluoroalkylation reactions of bicyclobutanes: direct sustainable pathways to functionalized bioisosteres for drug discovery
Green Chemistry·2024· 21 cited
Review and prospects of targeted therapies for Spleen tyrosine kinase (SYK)
Bioorganic & Medicinal Chemistry·2023· 14 citedOpen Access
Discovery of 3-(1H-benzo[d]imidazole-2-yl)-1H-pyrazol-4 -amine derivatives as novel and potent syk inhibitors for the treatment of hematological malignancies
European Journal of Medicinal Chemistry·2023· 8 citedOpen Access
Photoredox synthesis of Vicinal Dichloride using FeCl<sub>3</sub> as chlorine source
Asian Journal of Organic Chemistry·2023· 9 citedOpen Access
Discovery of 2-Amino-7-sulfonyl-7<i>H</i>-pyrrolo[2,3-<i>d</i>]pyrimidine Derivatives as Potent Reversible FGFR Inhibitors with Gatekeeper Mutation Tolerance: Design, Synthesis, and Biological Evaluation
Journal of Medicinal Chemistry·2022· 14 citedOpen Access
Dendritic polyethylene glycol-modified folate–nickel nanotubes as an efficient antitumor nano-metal medicine
Journal of Materials Science·2022· 1 cited
Discovery of 2H-benzo[b][1,4]oxazin-3(4H)-one derivatives as potent and selective CDK9 inhibitors that enable transient target engagement for the treatment of hematologic malignancies
European Journal of Medicinal Chemistry·2022· 9 citedOpen Access
Dendritic polyethylene glycol-modified folate-nickel nanotubes as an efficient antitumor nano-metal medicine
Research Square (Research Square)·2022Open Access
Discovery of 1-(5-(1H-benzo[d]imidazole-2-yl)-2,4-dimethyl-1H-pyrrol-3-yl)ethan-1-one derivatives as novel and potent bromodomain and extra-terminal (BET) inhibitors with anticancer efficacy
European Journal of Medicinal Chemistry·2021· 16 citedOpen Access
Discovery of a Potent FLT3 Inhibitor (LT-850-166) with the Capacity of Overcoming a Variety of FLT3 Mutations
Journal of Medicinal Chemistry·2021· 31 citedOpen Access
An Integrated Tumor Microenvironment Responsive Polymeric Micelle for Smart Drug Delivery and Effective Drug Release
Bioconjugate Chemistry·2021· 16 cited
Discovery of <i>N</i>-(4-(3-isopropyl-2-methyl-2<i>H</i>-indazol-5-yl)pyrimidin-2-yl)-4-(4-methylpiperazin-1-yl)quinazolin-7-amine as a Novel, Potent, and Oral Cyclin-Dependent Kinase Inhibitor against Haematological Malignancies
Journal of Medicinal Chemistry·2021· 18 citedOpen Access
The discovery of quinoline derivatives, as NF-κB inducing kinase (NIK) inhibitors with anti-inflammatory effects in vitro, low toxicities against T cell growth
Bioorganic & Medicinal Chemistry·2020· 15 citedOpen Access
Discovery of coumarin derivatives as potent and selective cyclin-dependent kinase 9 (CDK9) inhibitors with high antitumour activity
European Journal of Medicinal Chemistry·2020· 41 citedOpen Access
Redox-Neutral Borylation of Aryl Sulfonium Salts via C–S Activation Enabled by Light
Organic Letters·2019· 72 cited
Protein–ligand interaction-guided discovery of novel VEGFR-2 inhibitors
Journal of Biomolecular Structure and Dynamics·2019· 21 citedOpen Access
Protein–ligand interaction-guided discovery of novel VEGFR-2 inhibitors
Figshare·2019Open Access
Discovery of potent Pan-Raf inhibitors with increased solubility to overcome drug resistance
European Journal of Medicinal Chemistry·2018· 11 citedOpen Access
Transition-metal-free base catalyzed intramolecular cyclization of 2-ynylphenols for efficient and facile synthesis of 2-substituted benzo[<i>b</i>]furans
RSC Advances·2018· 26 citedOpen Access
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Frequent Co-authors

Tao Lu(35), Yadong Chen(17), Ding Du(15), Yanmin Zhang(9), Tao Lu(9), Yong Zhu(9), Hongmei Li(7), Yingyan Lu(6), Zhimin Zhang(6), Gaoyuan Zhu(6), Xiang Zhou(5), Junyu Xu(5), Chunqi Duan(5), Yue Wang(5), Ting Ran(4), Fei Jiang(4), Yu Jiao(4), Shihe Hu(4), Xinren Wang(4), Chenhe Liu(4)