Tuulia Vallius

Harvard University — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

13h-index905citations81works3.22yr avg
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Research Topics

Single-cell and spatial transcriptomics(34), Cell Image Analysis Techniques(25), Advanced Biosensing Techniques and Applications(21), Ovarian cancer diagnosis and treatment(16), Immunotherapy and Immune Responses(11)

Publications80 total

Harnessing Inflammatory Monocytes to Overcome Resistance to Anti-PD-1 Immunotherapy
2026Open Access
In vivo evidence for bleb-induced survival signaling in metastatic melanoma
2026Open Access
Mechanisms of tumor persistence in metastatic melanoma following successful immunotherapy
2025Open Access
Integrative single-cell and spatial mapping of oxidative stress response uncovers GCLC+ mesenchymal tumor cell state linked with favorable outcomes in triple negative breast cancer
2025Open Access
488 Integrative molecular and spatial analysis to reveal tumor intrinsic and extrinsic drivers of immunotherapy response in mucosal melanoma
Regular and Young Investigator Award Abstracts·2025Open Access
Multiomic profiling of a unique in-transit melanoma cohort identifies melanoma differentiation as predictor of tumor progression and therapy response
2025Open Access
Spatial determinants of tumor cell dedifferentiation and plasticity in primary cutaneous melanoma
2025· 3 citedOpen Access
Abstract 169: Tumor heterogeneity and differential pathway activation in melanoma: insights from spatial profiling of AXL and NGFR upregulated regions
Cancer Research·2025
Abstract 7152: High-dimensional, single-cell analysis and transcriptional profiling reveal novel correlatives of response to PARP inhibition plus PD-1 blockade in triple-negative breast cancer
Cancer Research·2025
Abstract 5014: Integrative molecular and spatial analysis to reveal tumor intrinsic and extrinsic drivers of immunotherapy response in mucosal melanoma
Cancer Research·2025
Abstract 158: Spatial heterogeneity of tumor cell states in primary cutaneous melanoma
Cancer Research·2025
PRAME Expression in Melanoma is Negatively Regulated by TET2-Mediated DNA Hydroxymethylation
Laboratory Investigation·2025· 2 citedOpen Access
Genomic Characteristics and Immune Dynamics of Tumor Progression in Melanoma with In-Transit Metastasis (ITM)
EJC Skin Cancer·2025Open Access
Chemotherapy induces myeloid-driven spatially confined T cell exhaustion in ovarian cancer
Cancer Cell·2024· 40 cited
92 High-dimensional, single-cell analysis and transcriptional profiling reveal novel correlatives of response to PARP inhibition plus PD-1 blockade in triple-negative breast cancer
Regular and Young Investigator Award Abstracts·2024· 1 citedOpen Access
1404 Unveiling the spatial landscape of persistent stable metastatic lesions in patients treated with anti-CTLA-4 or Anti-CTLA-4 + Anti-PD-1 therapy at single-cell resolution
Regular and Young Investigator Award Abstracts·2024Open Access
Quality control for single-cell analysis of high-plex tissue profiles using CyLinter
Nature Methods·2024· 13 citedOpen Access
1114P Deciphering unresectable in-transit metastasis in melanoma: Multi-modal and longitudinal insights
Annals of Oncology·2024
PRAME expression in melanoma is negatively regulated by TET2-mediated DNA hydroxymethylation
2024Open Access
SpatialCells: automated profiling of tumor microenvironments with spatially resolved multiplexed single-cell data
Briefings in Bioinformatics·2024· 4 citedOpen Access
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Frequent Co-authors

Peter K. Sorger(39), Christine G. Lian(23), Gëorge F. Murphy(23), Zoltan Maliga(22), Sandro Santagata(22), Ajit J. Nirmal(20), Roxanne J. Pelletier(20), Clarence Yapp(19), Connor A. Jacobson(16), Yu‐An Chen(16), Alyce A. Chen(15), Brian Quattrochi(14), Raquel Arias-Camison(14), Johanna Hynninen(14), Anniina Färkkilä(11), Sampsa Hautaniemi(10), Seija Grénman(9), Janae Davis(8), Elizabeth A. Mittendorf(8), Jennifer L. Guerriero(8)