Guido Tans

Medicine · Health Sciences

43h-index7.0kcitations114works0.02yr avg
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Research Topics

Blood Coagulation and Thrombosis Mechanisms(90), Coagulation, Bradykinin, Polyphosphates, and Angioedema(37), Hemophilia Treatment and Research(27), Venomous Animal Envenomation and Studies(24), Venous Thromboembolism Diagnosis and Management(16)

Publications109 total

Chemoselective Oxime Reactions in Proteins and Peptides by Using an Optimized Oxime Strategy: The Demise of Levulinic Acid
ChemBioChem·2013· 24 cited
Multactivase
Handbook of Proteolytic Enzymes·2012
Notecarin D Binds Human Factor V and Factor Va with High Affinity in the Absence of Membranes
Journal of Biological Chemistry·2011· 11 citedOpen Access
Increased tissue factor pathway inhibitor activity is associated with myocardial infarction in young women: results from the RATIO study
Journal of Thrombosis and Haemostasis·2011· 26 citedOpen Access
Factor XIIa regulates the structure of the fibrin clot independently of thrombin generation through direct interaction with fibrin
Blood·2011· 135 cited
Active Site-labeled Prothrombin Inhibits Prothrombinase in Vitro and Thrombosis in Vivo
Journal of Biological Chemistry·2011· 16 citedOpen Access
Combined formative and summative professional behaviour assessment approach in the bachelor phase of medical school: A Dutch perspective
Medical Teacher·2010· 28 citedOpen Access
Snake Venom Prothrombin Activators – The History
2010· 9 cited
Pregnancy‐associated changes in the hemostatic system in wild‐type and factor V Leiden mice
Journal of Thrombosis and Haemostasis·2008· 8 cited
Protein S is a cofactor for tissue factor pathway inhibitor
Thrombosis Research·2008· 40 cited
Re-evaluation of the role of the protein S-C4b binding protein complex in activated protein C-catalyzed factor Va-inactivation
Blood·2007· 79 citedOpen Access
Development of a calibrated automated thrombography based thrombin generation test in mouse plasma
Journal of Thrombosis and Haemostasis·2007· 72 cited
The Role of Thrombin Exosites I and II in the Activation of Human Coagulation Factor V
Journal of Biological Chemistry·2007· 36 citedOpen Access
PROTEIN S-C4BP COMPLEX STIMULATES ACTIVATED PROTEIN C-MEDIATED INACTIVATION AT R306 BUT INHIBITS INACTIVATION AT R506 IN FACTOR VA
Journal of Thrombosis and Haemostasis·2007
Expression of Allosteric Linkage between the Sodium Ion Binding Site and Exosite I of Thrombin during Prothrombin Activation
Journal of Biological Chemistry·2007· 24 citedOpen Access
Effect of oral contraceptives on thrombin generation measured via calibrated automated thrombography
Thrombosis and Haemostasis·2007· 92 cited
5B.2 Mechanism of hormonal therapy related thrombosis
Thrombosis Research·2007
Venous thrombosis and oral contraceptives: current status
Women s Health·2006· 15 citedOpen Access
Protein S stimulates inhibition of the tissue factor pathway by tissue factor pathway inhibitor
Proceedings of the National Academy of Sciences·2006· 318 citedOpen Access
Protein S levels modulate the activated protein C resistance phenotype induced by elevated prothrombin levels
Thrombosis and Haemostasis·2006· 24 cited
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Frequent Co-authors

Jan Rosing(45), Stella Thomassen(19), H.C. Hemker(12), Gerry A. F. Nicolaes(10), Joyce Curvers(7), Elisabetta Castoldi(6), José W.P. Govers‐Riemslag(5), Lico Hoekema(5), Karly Hamulyák(4), Tilman M. Hackeng(4), John H. Griffin(4), Joost C.M. Meijers(4), Bonno N. Bouma(4), H. M. Bakker(4), Domenico Girelli(4), R.F.A. Zwaal(3), Katalin Váradi(3), Rogier M. Bertina(3), Frits R. Rosendaal(3), Kristin Seré(2)